research Hox in the Niche Controls Hair Heterogeneity
Hox genes control hair growth patterns in mammals by regulating stem cell activity in the skin.
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research Evidence That the Satin Hair Mutant Gene Foxq1 Is Among Multiple and Functionally Diverse Regulatory Targets for Hoxc13 During Hair Follicle Differentiation
The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.
research Identification of novel glucocorticoid receptor-regulated genes involved in epidermal homeostasis and hair follicle differentiation
The study identified 173 genes regulated by the glucocorticoid receptor (GR) in mouse skin using a transgenic mouse model overexpressing GR in epidermal basal cells and hair follicles. Key findings included the identification of hair keratin (krt) and keratin-associated protein (krtap) genes, as well as hox genes, as being regulated by GR, suggesting a role in hair follicle morphogenesis. The study also found that GR repressed genes related to cell growth, such as fosb and c-fos, highlighting its antiproliferative effects. These findings provided insights into the role of glucocorticoids in skin physiology and potential implications for hair disorders.
research Specific Ectodermal Enhancers Control the Expression of Hoxc Genes in Developing Mammalian Integuments
The HoxC gene cluster and its enhancers are essential for developing hair and nails in mammals.
research Distinct Mechanisms Underlie Pattern Formation in the Skin and Skin Appendages
Different processes create patterns in skin and things like hair and feathers.
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1 / 1 resultscommunity Is it possible for androgenic alopecia to begin at early adolescent years?
Hair loss can begin in early adolescence and cause mental anguish. Treatments mentioned include eating cruciferous vegetables, engaging in physical activity, and maintaining scalp hygiene.