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GlossaryHomeobox Genes

regulatory genes controlling body plan and organ development

Homeobox genes, often referred to as Hox genes, are a group of regulatory genes that play a crucial role in determining the body plan and the formation of tissues and organs during early embryonic development. They contain a specific DNA sequence called the homeobox, which encodes a protein domain (the homeodomain) that can bind to DNA and regulate the expression of other genes. This precise regulation ensures that body structures form in the correct locations.

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research Hox Genes in Development and Beyond

83 citations , January 2023 in “Development”

Hox genes are crucial for development and tissue maintenance, affecting structures and functions throughout life.

research Hox in the Niche Controls Hair Heterogeneity

4 citations , October 2018 in “Cell Stem Cell”

Hox genes control hair growth patterns in mammals by regulating stem cell activity in the skin.

research MLL Histone Methylases in Estrogen-Mediated Regulation of HOX Genes Involved in Hair Follicle Development and Leukemia

3 citations , April 2010 in “The FASEB Journal”

Estrogen and MLL enzymes work together to regulate genes important for hair growth and leukemia.

Evidence That the Satin Hair Mutant Gene Foxq1 Is Among Multiple and Functionally Diverse Regulatory Targets for Hoxc13 During Hair Follicle Differentiation

research Evidence That the Satin Hair Mutant Gene Foxq1 Is Among Multiple and Functionally Diverse Regulatory Targets for Hoxc13 During Hair Follicle Differentiation

65 citations , July 2006 in “Journal of biological chemistry/The Journal of biological chemistry”

The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.

research Identification of Novel Glucocorticoid Receptor-Regulated Genes Involved in Epidermal Homeostasis and Hair Follicle Differentiation

19 citations , September 2007 in “The Journal of Steroid Biochemistry and Molecular Biology”

Glucocorticoid receptors help regulate genes important for skin health and hair growth.

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community Is it possible for androgenic alopecia to begin at early adolescent years?

in Chat 70 upvotes 2 years ago

Hair loss can begin in early adolescence and cause mental anguish. Treatments mentioned include eating cruciferous vegetables, engaging in physical activity, and maintaining scalp hygiene.