15 citations
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December 2020 in “Pharmacology Research & Perspectives” This review discusses targeting host cell proteases as a novel approach to inhibit SARS-CoV-2 infection, highlighting transcriptional modulation and enzymatic inhibition as promising therapeutic strategies, but it reports no new clinical findings.
May 2017 in “Journal of The American Academy of Dermatology” PLAU and SerpinB2 affect cell death differently in various forms of leprosy and could be targets for new treatments.
18 citations
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September 1990 in “Veterinary Dermatology” This study in SPF lambs found that primary and secondary orf virus infections trigger similar skin responses, but the primary infection caused a more severe and prolonged reaction.
48 citations
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January 2024 in “Immune Network” This review highlights recent insights into how IL-15 influences T cell responses and contributes to immunopathogenesis in various diseases, suggesting its crucial role in TCR-independent activation and potential in optimizing therapeutic strategies.
5 citations
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December 2022 in “Viruses” This review highlights recent insights into using antiandrogens as preventive and therapeutic measures against COVID-19, emphasizing their role in blocking viral infection by modulating androgen-mediated host protease TMPRSS2 and cell entry protein ACE2, with varying success in clinical trials.