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research The influence of Castanea sativa Mill. flower extract on hormonally and chemically induced prostate cancer in a rat model

7 citations , January 2021 in “Food & Function”

In this animal study, Castanea sativa Mill. flower extract did not significantly affect prostate tumorigenesis but demonstrated antioxidant and anti-inflammatory effects on the prostate and liver.

research New Methods of Endocrine Management of Prostatic Cancer

67 citations , January 1987 in “The Journal of urology/The journal of urology”

New hormonal therapies can help treat advanced prostate cancer but may cause testicular issues.

research Endocrinology of the Aging Prostate: Current Concepts

21 citations , February 2021 in “Frontiers in Endocrinology”

This review explores the potential impact of hormonal changes during aging on benign prostate hyperplasia-related urinary symptoms and metabolic syndrome, highlighting the hypothesis of a male PCOS-equivalent but reports no new clinical results.

research Hormonal prevention of prostate cancer

28 citations , January 2003 in “Urologic oncology”

This review discusses the hormonal influences on prostate carcinogenesis and notes ongoing trials investigating whether finasteride could reduce prostate cancer incidence by inhibiting dihydrotestosterone synthesis, but it reports no new results.

research Key targets of hormonal treatment of prostate cancer. Part 2: the androgen receptor and 5α-reductase

29 citations , July 2009 in “BJU international”

This review examines the pharmacological properties and potential clinical benefits of 5α‐reductase inhibition in prostate cancer but reports no new research findings.

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community Fresh off the press: Dutasteride may cause chronic infertility

in Research/Science 643 upvotes 1 year ago

Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

community Doctor says i shouldn't take fin because its "hormonal"

102 upvotes 2 years ago

A user in Turkey was advised by a dermatologist to avoid finasteride due to its hormonal effects and was prescribed minoxidil, shampoo, and vitamins instead. The user is considering seeking another doctor's opinion or buying finasteride directly from a pharmacy.

community Why is Finasteride seen as “scary” for men, but hormonal birth control is totally normalized for women?

in Finasteride/Dutasteride 757 upvotes 1 year ago

Finasteride is seen as risky for men due to side effects like erectile dysfunction, while hormonal birth control for women is normalized despite its side effects. The discussion points out a double standard influenced by societal and gender norms.

community Minoxidil is a 5ar inhibitor according to research

150 upvotes 11 months ago

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

community EU Shouldn't Ban Fin & Dut: PFS is NOT REAL.

10 upvotes 1 year ago

Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.

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