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Glossary Hormonal Effects

changes in body functions due to hormone activity

Hormonal effects refer to the changes in the body that occur due to the action of hormones, which are chemical messengers produced by glands in the endocrine system. These effects can influence various physiological processes, including growth, metabolism, mood, and reproductive functions. For example, fluctuations in hormones like estrogen and testosterone can impact hair growth and contribute to conditions such as alopecia.

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Research

5 / 1000+ results

research Acne: a side‐effect of masculinizing hormonal therapy in transgender patients

57 citations , August 2018 in “British Journal of Dermatology”

This review discusses the pathogenesis and treatment of acne in transgender men on testosterone therapy and reports no new clinical results, emphasizing the need for tailored guidelines.

Individual Article: USCOM V: A Practical Algorithm for the Prevention and Treatment of Cutaneous Side Effects of Hormonal Cancer Therapy

research INDIVIDUAL ARTICLE: USCOM V: A Practical Algorithm for the Prevention and Treatment of Cutaneous Side Effects of Hormonal Cancer Therapy

March 2025 in “Journal of Drugs in Dermatology”

This study developed a physician-guided algorithm to manage cutaneous adverse events from hormonal therapy in cancer patients, aiming to reduce treatment interruptions and enhance quality of life.

research Side effects of common acne treatments

38 citations , November 2012 in “Expert Opinion on Drug Safety”

This article reviews different acne treatments and emphasizes the importance of being aware of their potential side effects, but reports no new clinical results.

research Treatment Strategies for Cutaneous and Oral Mucosal Side Effects of Oncological Treatment in Breast Cancer: A Comprehensive Review

5 citations , August 2025 in “Biomedicines”

This review highlights the significant impact of cutaneous and oral mucosal adverse events on patients undergoing breast cancer treatment, emphasizing the need for early detection and comprehensive management to maintain treatment adherence and enhance patient care.

GLP-1 Receptor Agonists and Skin Health: Exploring Dermatologic Side Effects and Therapeutic Interventions

research GLP-1 RAs and Skin Health: Exploring Dermatologic Side Effects and Therapeutic Interventions

June 2025

This review highlights concerns about dermatological side effects linked to rapid weight loss from glucagon-like peptide-1 receptor agonists used for type 2 diabetes and obesity treatment, such as skin laxity, decreased collagen, and hair loss, emphasizing the importance of managing these while retaining metabolic benefits.

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Learn

7 / 14 results

learn Estradiol

Can Estradiol cause side effects in people without a hormonal imbalance? Estradiol can cause side effects even in hormonally balanced individuals.

learn Follistatin

How does follistatin compare to finasteride or dutasteride for treating androgenic alopecia? Finasteride and dutasteride are prescription drugs with large controlled trials showing they lower DHT and slow androgenic hair loss, at the cost of documented hormonal side effects; follistatin targets a different, regenerative pathway but has only one small phase 1 human trial behind it, so it is experimental with unknown safety rather than a comparable alternative.

learn Alfatradiol

a synthetic estrogen used topically as an anti-androgen

learn Finasteride

Frontline, gold standard treatment for combatting androgenic alopecia

learn Bicalutamide

a nonsteroidal anti-androgen, most commonly used orally for women

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Community Join

5 / 726 results

community Finasteride and hormonal tests

in Finasteride/Dutasteride 8 months ago

A user has been taking finasteride 1mg for 10 years without side effects but is concerned about high estradiol levels affecting weight loss. Another user suggests using estradiol blockers under medical supervision to manage the levels.

community Why is Finasteride seen as “scary” for men, but hormonal birth control is totally normalized for women?

in Finasteride/Dutasteride 757 upvotes 1 year ago

Finasteride is seen as risky for men due to side effects like erectile dysfunction, while hormonal birth control for women is normalized despite its side effects. The discussion points out a double standard influenced by societal and gender norms.

community Starting 5mg Finasteride split into 1.25mg. Is the hormonal fluctuation risk real?

in Treatment 1 upvotes 5 months ago

An 18-year-old is considering splitting 5mg Finasteride pills into 1.25mg doses to save money, but is concerned about potential hormonal fluctuations and side effects due to his age. Users advise caution, suggest consulting a doctor, and recommend considering lower or less frequent doses.

community DHT Isn't (Directly) Important

101 upvotes 1 year ago

Finasteride's potential side effects, especially sexual dysfunction, are discussed, with emphasis on hormonal balance between testosterone and estradiol. Users share experiences with finasteride, minoxidil, and dutasteride, highlighting the variability in side effects and the influence of mindset and lifestyle.

community Why some people experience problems on Finasteride/Dutasteride (my theory)

in Research/Science 18 upvotes 9 months ago

Some people have side effects from finasteride and dutasteride due to hormonal predisposition, especially if DHT dominant. Alternatives like RU58841, Pyrilutamide, and Breezula are suggested to target scalp androgen receptors without altering overall hormones.

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