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      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Sulforaphane

      compound from cruciferous vegetables has some mild effects on DHT

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      community second shed on dutasteride, but a woman

      in Finasteride/Dutasteride  2 upvotes 3 weeks ago
      A woman experiencing hormonal hair loss is on dutasteride and bicalutamide, which initially improved her hair, but she is now experiencing a second shedding phase with significant short hair loss. Despite normal hormone levels and no deficiencies, she is unsure if this shedding is normal and seeks advice.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  83 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2452 upvotes 4 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community DHT Isn't (Directly) Important

      in Research/Science  100 upvotes 3 months ago
      Finasteride's potential side effects, especially sexual dysfunction, are discussed, with emphasis on hormonal balance between testosterone and estradiol. Users share experiences with finasteride, minoxidil, and dutasteride, highlighting the variability in side effects and the influence of mindset and lifestyle.