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GlossaryHistopathological

microscopic examination of tissue to study disease manifestations

Histopathological refers to the microscopic examination of tissue in order to study the manifestations of disease. This process, also known as histopathology, involves analyzing tissue samples under a microscope to identify abnormalities, such as those seen in conditions like alopecia, where hair follicles might show specific patterns of inflammation or damage.

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research A Cross-Sectional Study of Clinical, Dermoscopic, Histopathological, and Molecular Patterns of Scalp Melanoma in Patients With or Without Androgenetic Alopecia

September 2022 in “Scientific Reports”

Scalp melanoma is more common and easier to diagnose early in people with androgenetic alopecia due to sun damage.

research Trichoscopy: A New Frontier for the Diagnosis of Hair Diseases

5 citations, October 2012 in “Expert Review of Dermatology”

Trichoscopy is a useful tool for diagnosing hair and scalp diseases without needing skin biopsies.

research Comparison of the Effects of Aloe Vera Gel and Coconut Oil on the Healing of Open Wounds in Rats

January 2023 in “Veterinarni Medicina”

Aloe vera gel helps heal open wounds better than coconut oil.

research Validity and Advantages of Three-Dimensional High-Frequency Ultrasound in Dermatological Evaluation

January 2025 in “Diagnostics”

3D high-frequency ultrasound can help diagnose skin and hair conditions without invasive biopsies.

research Clinicopathological Characteristics of Fibrosing Alopecia in a Pattern Distribution: A Single-Center, Retrospective Study

April 2023 in “Journal of Investigative Dermatology”

The study suggests fibrosing alopecia in a pattern distribution has distinct features and may vary by race.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 828 upvotes 5 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 1 year ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.