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Feasibility of Repairing Skin Defects by VEGF165 Gene-Modified iPS-HFSCs Seeded on a 3D Printed Scaffold Containing Astragalus Polysaccharide

research Feasibility of repairing skin defects by VEGF₁₆₅ gene‐modified iPS‐HFSCs seeded on a 3D printed scaffold containing astragalus polysaccharide

1 citations , June 2023 in “Journal of Cellular and Molecular Medicine”

This study observed that tissue-engineered skin, using VEGF165 gene-modified cells embedded in astragalus polysaccharide-containing 3D printed scaffolds, enhanced early vascularization, and collagen and hair follicle regeneration, leading to improved skin repair in nude mice with full skin defects.

Synergism Between Tocotrienol and Injectable Platelet-Rich Fibrin in Hair Follicle Stem Cells Proliferation: An In Vitro Study

research Synergism between Tocotrienol and i-PRF in HFSCs proliferation: an in-vitro study

July 2023 in “Research Square (Research Square)”

In an in-vitro study, researchers found that a specific concentration of Aloe Vera combined with injectable platelet-rich fibrin (i-PRF) significantly increased hair follicle stem cell proliferation compared to Aloe Vera or i-PRF alone, indicating potential benefits for alopecia treatment.

Cross-Interactions of BMP and WNT Signaling Pathways Attenuate Androgen Effect on Hair Follicle Stem Cell Differentiation

research 592 Cross-interactions of BMP and WNT signaling pathways attenuate androgen effect on HFSC differentiation

September 2019 in “Journal of Investigative Dermatology”

This study found that BMPs can counteract the inhibitory effects of androgens on hair follicle stem cell differentiation, highlighting their critical role in the pathway dysregulation seen in androgenetic alopecia.

research Fabricating Composite Cell Sheets for Wound Healing: Cell Sheets Based on the Communication Between BMSCs and HFSCs Facilitate Full-Thickness Cutaneous Wound Healing

12 citations , November 2023 in “Tissue Engineering and Regenerative Medicine”

research 803 Taxane chemotherapy induces epigenetic changes and premature senescence in human scalp hair follicles

July 2024 in “Journal of Investigative Dermatology”

Taxane chemotherapy can cause permanent hair loss by damaging hair follicles and altering their DNA.

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Community Join

5 / 33 results

community Can somebody tell my why Scube3 is not going to work?

7 upvotes 2 years ago

The conversation discusses concerns about Scube3's effectiveness and potential cancer link. It questions whether Scube3 can regrow hair and how well it works according to researchers.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 3 years ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community Tazarotene shows strong standalone hair regrowth potential, not just a Minoxidil enhancer. Backed by VEGF, HF regeneration, and angiogenesis pathways. Here’s why.

135 upvotes 1 year ago

Tazarotene shows potential as a standalone treatment for hair regrowth by stimulating new hair follicle formation and promoting angiogenesis, similar to microneedling effects. It can be used topically without minoxidil, but users should start with a low concentration to avoid irritation.

community My understanding of how androgenetic alopecia works (plus FIN and DUT)

18 upvotes 4 years ago

Androgenetic alopecia is affected by scalp DHT levels, not sensitivity, with treatments like finasteride and dutasteride aiming to optimize these levels. Personalized DHT management is crucial for effective hair growth.

community Do you Have Poor Posture? Maybe Contributing to Hair Loss , Esp Diffuse Thinning

in Research/Science 16 upvotes 3 weeks ago

Correcting posture may improve hair health by enhancing blood circulation and reducing side effects like bloating and sexual issues. The user has been using minoxidil and finasteride for two years with underwhelming results and is exploring posture correction as a potential aid.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn HT-B

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