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research Safety and quality of life of CDK4/6 inhibitors therapy for hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: a multicenter cross-sectional survey in China

1 citations , May 2025 in “BMC Cancer”

In this study, the researchers found that different CDK4/6 inhibitors used in treating HR+/HER2- advanced breast cancer have varying safety profiles and impacts on patient quality of life.

research 5-Bromo-2′-deoxyuridine induced effluvium via p53-mediated CD326-positive keratinocyte apoptosis in C57BL/6 mice

August 2016 in “Journal of Dermatology”

This research successfully established a novel mouse model for anagen effluvium using BrdU treatment, which induced hair loss and pathological changes mimicking human symptoms.

research Study of SARS-CoV-2 in semen and urine samples of a volunteer with positive naso-pharyngeal swab

198 citations , April 2020 in “Journal of Endocrinological Investigation”

This study found no SARS-CoV-2 RNA in the semen and urine of a COVID-19 patient, suggesting possible viral clearance or absence in these fluids.

5-Alpha-Reductase Inhibitors Reduce Remission Time of COVID-19: Results From a Randomized Double-Blind Placebo-Controlled Interventional Trial in 130 SARS-CoV-2 Positive Men

research 5-Alpha-Reductase Inhibitors Reduce Remission Time of COVID-19: Results From a Randomized Double Blind Placebo Controlled Interventional Trial in 130 SARS-CoV-2 Positive Men

5 citations , November 2020 in “medRxiv (Cold Spring Harbor Laboratory)”

In this study, the authors reported that dutasteride significantly reduced total remission time for COVID-19 symptoms in men compared to placebo, especially for fatigue and loss of taste or smell.

research Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells

8 citations , July 2022 in “International Journal of Molecular Sciences”

This study found that in estrogen receptor-positive breast cancer cells, 17β-estradiol repressed polyamine oxidase transcription by interacting with AP-1 sites on its promoter.

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community 12 months of Min 2.5mg and Fin 1mg daily- A positive experience

10 upvotes 5 months ago

A user shared a positive experience using Minoxidil (2.5mg) and Finasteride (1mg) daily for hair loss, noting initial side effects like numbness and reduced alcohol tolerance but overall hair improvement after a year. They also used rosemary shampoo and supplements, emphasizing the importance of consulting a dermatologist and maintaining a healthy lifestyle.

community 2 months in, I think it's working

822 upvotes 7 months ago

The user reported positive progress in hair regrowth after two months using finasteride, topical minoxidil, microneedling, and ketoconazole, later switching to dutasteride. Some users doubted the authenticity of the results, while others were impressed and encouraged by the progress.

community 2 months Minoxidil / Finasteride from RO May 8 - July 17

in Minoxidil 165 upvotes 1 year ago

The user experienced positive results with topical Minoxidil 6%, Finasteride 0.3%, and Tretinoin 0.025% over two months, with improved hair density and no significant side effects except for a dry, itchy scalp. The user uses a biotin shampoo and conditioner to manage scalp issues and applies the treatment once daily.

community Finasteride only - 2 years progress

in Progress Pictures 284 upvotes 10 months ago

The user experienced positive hair regrowth using finasteride for two years, with no side effects, and recently added minoxidil foam to address temple volume. Other users shared similar experiences with finasteride, noting varying results and some concerns about side effects, but overall satisfaction with hair maintenance.

community Progress- 2 years on fin 1mg/day (27yo)

in Progress Pictures 469 upvotes 1 year ago

A user shared their positive experience with finasteride, noting significant hair regrowth over two years without using other treatments. They reported initial brain fog but no other side effects, and others in the conversation expressed encouragement and shared their own experiences with finasteride.

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