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GlossaryHematopoietic Stem Cells

produce all types of blood cells in bone marrow

Hematopoietic Stem Cells (HSCs) are a type of stem cell found in the bone marrow that are responsible for producing all the different types of blood cells, including red blood cells, white blood cells, and platelets. These cells have the unique ability to both self-renew, creating more HSCs, and differentiate into various specialized blood cells, making them crucial for maintaining a healthy and functional blood system.

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research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche

6 citations , May 2013 in “PloS one”

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

research Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair

24 citations , May 2016 in “Stem Cell Reviews and Reports”

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

research Fatal Autoimmunity Results from the Conditional Deletion of Snai2 and Snai3

8 citations , February 2015 in “Cellular immunology”

Deleting Snai2 and Snai3 causes fatal autoimmunity.

research Activation of Wnt Signaling in Hematopoietic Regeneration

49 citations , February 2008 in “Stem Cells”

Wnt10b helps blood stem cells grow after injury.

research 25 Years of Epidermal Stem Cell Research

55 citations , March 2012 in “Journal of Investigative Dermatology”

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

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community Painkillers May Block Minoxidil

in Research/Science 14 upvotes 5 months ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.