22 citations
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February 2013 in “Wound Repair and Regeneration” Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.
5 citations
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February 2022 in “International Journal of Molecular Sciences” Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.
89 citations
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January 2009 in “Advances in Clinical Chemistry” Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
29 citations
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September 2012 in “Birth Defects Research” Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.
32 citations
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January 2005 in “Advances in Biochemical Engineering / Biotechnology” Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.