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Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus Acutissima Cortex

research Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus Acutissima Cortex

37 citations, January 2015 in “Evidence-based Complementary and Alternative Medicine”

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

research MEK and BRAF Inhibitors Augment the Production and Accumulation of Sebum in Hamster Sebocytes

April 2016 in “Journal of Investigative Dermatology”

MEK and BRAF inhibitors increase sebum production and accumulation, which could cause acne-like side effects.

research Expression of Steroidogenic Enzymes in Human Sebaceous Glands

25 citations, June 2014 in “Journal of Endocrinology/Journal of endocrinology”

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Evaluation of the Effect of Plant Mixture Ethanol Extracts Containing Biota Orientalis L. Extract on Suppression of Sebum in Cultured Sebocytes and on Stimulation of Growth of Keratinocytes Co-cultured with Hair Papilla Cells

research Evaluation of the Effect of Plant Mixture Ethanol Extracts Containing Biota Orientalis L. Extract on Suppression of Sebum in Cultured Sebocytes and on Stimulation of Growth of Keratinocytes Co-cultured with Hair Papilla Cells

4 citations, August 2017 in “Cosmetics”

The extract reduced sebum production and promoted hair growth.

research Lipid Droplets And Associated Proteins In Sebocytes

24 citations, November 2015 in “Experimental Cell Research”

Sebum from sebocytes is important for skin health and linked to conditions like acne and hair loss.

View more "hamster sebocytes" in research →

Community Join

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community Why a lot of people seems to hate on topical fin even though it suppresses more scalp dht?

in Chat 20 upvotes 1 month ago

Topical finasteride may reduce more scalp DHT but is seen as inconsistent and messy compared to oral finasteride. Users report mixed results with both forms, with some preferring oral for its convenience and consistent dosing, while others find topical effective but harder to apply.

community 1 year and 3 months on Finasteride. No side effects.

in Progress Pictures 1 year ago

A user happy with their 1 year and 3 months of finasteride use with no side effects, which has resulted in recovery of their hairline. Other users have responded with congratulations, questions, and caution against using the medication at such a young age.

community I am having Success with RU58841 and 1mm Derma Roller

in Microneedling 19 upvotes 2 years ago

A user reported success with RU58841 and a 1mm derma roller for hair regrowth, noting significant improvement in hair density and reduced scalp visibility. They also mentioned using minoxidil and black castor oil in the past, with mixed results.

community bye fellas, it’s time to quit this sub

in Progress Pictures 810 upvotes 7 months ago

A user successfully improved their hairline after 15 months using topical minoxidil and dutasteride. Some commenters question the necessity of treatment given the user's original hair condition, while others support early intervention.