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research Kinetics and Equilibrium of Solute Diffusion into Human Hair

8 citations , July 2012 in “Annals of biomedical engineering”

This study found that the uptake of molecules by hair is influenced by both hydrophobic and ionic charge interactions, with binding affinity decreasing as pH approaches the solute's dissociation constant.

research Investigation of drug partition property in artificial sebum

33 citations , June 2007 in “International Journal of Pharmaceutics”

This study found that the sebum partition coefficient (K(sebum)) for some drugs differs from the stratum corneum partition coefficient (K(sc)), indicating its importance for targeted drug delivery into hair and sebaceous follicles.

research In-vitro permeation of drugs into porcine hair follicles: is it quantitatively equivalent to permeation into human hair follicles?

19 citations , January 2008 in “Journal of Pharmacy and Pharmacology”

This study found that porcine skin serves as a reliable model for studying drug absorption into human hair follicles, showing a strong correlation in follicular drug absorption between porcine and human skin.

research Determination of Solute Diffusion Properties in Artificial Sebum

6 citations , May 2019 in “Journal of pharmaceutical sciences”

This study found that diffusion coefficients of chemicals in artificial sebum are significantly higher than those in stratum corneum lipids, suggesting the hair follicle may significantly contribute to transdermal permeation.

research A Composite Model for the Transport of Hydrophilic and Lipophilic Compounds Across the Skin: Steady-State Behavior

32 citations , September 2018 in “Journal of pharmaceutical sciences”

This study extended a skin diffusion model to include a porous pathway, effectively explaining the permeability of both polar and lipophilic solutes through the stratum corneum.

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community Minoxidil is highly toxic to pets — help push for proper labeling [Petition]

in Minoxidil 251 upvotes 1 year ago

Minoxidil is highly toxic to pets, particularly cats and dogs, and there is a call for proper labeling to warn pet owners. Despite some skepticism about the effectiveness of petitions, many agree that awareness and caution are necessary to prevent accidental poisoning.

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

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