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research Examination of the Elemental Composition of Hair in Cholelithiasis, Kidney Stone, Hypertension and Diabetes by Scanning Electron Microscopy and Energy Dispersive Spectrometry SEM/EDS

9 citations , January 2014 in “Journal of analytical & bioanalytical techniques”

This study assessed whether the elemental composition of human hair could serve as a marker for kidney stones, cholelithiasis, hypertension, and diabetes, but it reports only variations in element content along hair regions.

research Recognition of the ultrastructure of the hair follicle of Cashmere goats under the transmission electron microscope

January 2015 in “Chinese Veterinary Science”

This study observed distinct changes in the ultrastructure of Hexi cashmere goat hair follicles throughout the year, highlighting stages with specific cellular and structural characteristics.

research Some electron microscope observations on hardening in the human hair follicle

25 citations , October 1962 in “Journal of Ultrastructure Research”

The hair follicle structure is more complex than thought, with new findings on protein formation.

research Outer root sheath keratinization in anagen and catagen of the mammalian hair follicle. A seventh distinct type of keratinization in the hair follicle: trichilemmal keratinization.

59 citations , August 1981 in “PubMed”

This study describes trichilemmal keratinization as a distinct process of hair follicle keratinization that occurs in specific areas of the outer root sheath, illustrated using electron microscopy on dog hair.

research Hair Casts: A Clinical and Electron Microscopic Study

24 citations , December 1990 in “Pediatric Dermatology”

This study observed that hair casts, seen in girls with tightly drawn hairstyles, may result from local circulatory disturbances and scalp inflammation.

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community Hair loss research focused on chemistry for decades because we misunderstood the mechanics of growth.

51 upvotes 7 months ago

Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 4 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

103 upvotes 4 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community How much DHT causes hair loss ?

in Finasteride/Dutasteride 2 upvotes 10 months ago

The user is taking 2.5 mg dutasteride and 5% minoxidil but is not seeing hair regrowth, and is considering adding RU58841. They are experiencing fatigue and low MCV/MCH, possibly related to dutasteride, and are advised to be patient, consider microneedling, and check for iron deficiency.

community How true is the statement: dead follicles don't grow back?

112 upvotes 1 year ago

Hair follicles usually go dormant rather than die, and treatments like finasteride, minoxidil, and hormone therapy can sometimes reactivate them, though results vary. Complete regrowth is rare, especially in long-term bald areas, but some individuals see significant improvement with these treatments.

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