21 citations
,
March 2003 in “Clinical and Experimental Dermatology”
This study found two recurrent missense mutations in the hHb6 gene associated with monilethrix in families from Russia and Colombia, supporting their role in this hair disorder worldwide.
This study identified a missense mutation in the rat Desmoglein 4 gene, causing abnormal hair shaft development in lanceolate hair mutant rats by disrupting a critical calcium binding site.
29 citations
,
July 2015 in “Journal of Medical Genetics”
This study identified a new gene involved in woolly hair by linking a homozygous variant in KRT25 to autosomal recessive woolly hair in two Pakistani families.
A user is experiencing severe hair thinning and insecurity due to potential iron deficiency and is seeking advice on regrowth. A suggestion was made to address low ferritin levels with iron supplements and consult a dermatologist for further evaluation.
The user noticed hair loss in 2019 and started using finasteride in July 2021, later adding Minoxidil, derma rolling, and Nizoral, but saw no regrowth. They recently began taking vitamins D, C, iron, and zinc, while another user suggested trying dutasteride, though it may have more side effects.
The user has been treating hair loss for nine years using finasteride, oral minoxidil, and microneedling, with significant improvements in hair density and texture. They emphasize the importance of consistent treatment, physical health, and lifestyle changes in achieving these results.
The user started finasteride in 2017, added oral minoxidil in 2024, and began microneedling in 2025, achieving significant hair regrowth without side effects. They recommend using all three treatments together for the best results.
Missing 15 days of finasteride and minoxidil may cause some hair loss, but resuming treatment should help regrow hair. It's important not to miss doses to avoid potential setbacks.
Does castor oil make hair grow or is it just a myth?There is no published human trial showing castor oil grows hair. It can make hair look and feel better by reducing breakage and adding shine, which is easily mistaken for growth, and it is not approved anywhere as a hair loss treatment.
RU58841: Is it easy to get or is it an impossible mission?RU58841 is not approved as a medicine anywhere and is sold only as an unregulated 'research chemical', so identity and purity are unverified. There is no published human trial for hair loss, and a small 2026 study found it reaches the blood after scalp use.