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research “Two-Cell Assemblage” Assay: A Simple in vitro Method for Screening Hair Growth-Promoting Compounds

5 citations , November 2020 in “Frontiers in Cell and Developmental Biology”

This study introduced a simple and reliable in vitro assay capable of large-scale simultaneous screening of hair growth-promoting compounds using a 3D co-culture system of human dermal papilla and outer root sheath cells.

research 3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid (TCQA)

2 citations , June 2022 in “Cells”

The study found that growing dermal papilla cells in 3D spheroids enhances their activity with hair growth-promoting agents, such as minoxidil and TCQA, compared to traditional 2D cultures.

research Bioactive Compound-Loaded Nanocarriers for Hair Growth Promotion: Current Status and Future Perspectives

October 2023 in “Plants”

This review highlights various plant-based and herbal treatments that reportedly help prevent hair loss and encourage hair growth. It also explores the molecular mechanisms, identified plant compounds, recent technologies such as nanoarchitectonics, and patents related to hair growth promotion.

research Promotion of hair growth by newly synthesized ceramide mimetic compound

8 citations , July 2017 in “Biochemical and biophysical research communications”

This study reported that the pseudoceramide bis-oleamido isopropyl alcohol (BOI) promotes hair growth in ex vivo cultured human hair follicles, likely by enhancing sphingolipid synthesis in dermal papilla cells.

research Antioxidative and Hair-growth-promotion Effects of a Fermented Compound Composed of Five Materials

June 2018 in “JoLS Journal of Life Sciences”

The fermented mixture may help hair growth and has antioxidative benefits.

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Community Join

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community Lion Mane Part 2: Microneedling with Topicals, beneficial compounds, maybe?

1 upvotes 2 years ago

The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.

community TDM-105795 phase 2 results are in!

27 upvotes 2 years ago

TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

community GT20029 Big Phase 2 Update Results!

53 upvotes 9 months ago

GT20029 showed promising results for hair growth in a Phase II trial, with the 1.0% twice-weekly regimen being the most effective. Some users expressed skepticism and humor about the product's effects and market availability.

community Veradermics VDPHL01 Topline Results for Extended-Release Oral Minoxidil

75 upvotes 4 months ago

Extended-release oral minoxidil (VDPHL01) shows promising results for hair growth with improved safety, achieving significant hair count increases and minimal side effects compared to placebo. The treatment is designed to maintain effective concentrations while reducing side effects, making it a safer option for those who cannot tolerate standard minoxidil.

community Pelage PP405: New Hair Growth from Inactive Follicular Units - Phase 2a results at AAD 2026

1080 upvotes 5 months ago

PP405, a topical treatment, shows promise for hair growth by activating inactive follicles, with 66% of participants experiencing positive results. The treatment is well-tolerated and may proceed directly to Phase 3 trials, offering a potential alternative to minoxidil and finasteride.

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Learn

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learn Stemoxydine

chemical from L'Oreal that encourages hair to enter growth phase

How does stemoxydine help stimulate new hair growth on the scalp? Stemoxydine stimulates new hair growth by promoting hair follicles to transition from the resting phase to the active growth phase.

learn KY19382

compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

learn GT20029

research compound made to degrade androgen receptors in scalp

learn Procyanidin

bioflavonoid found in plants with antioxidant and hair stimulating properties

What is Procyanidin, and how does it encourage hair growth at the follicle level? Procyanidin stimulates hair growth by promoting cell proliferation in hair follicles.

learn Sulforaphane

compound from cruciferous vegetables has some mild effects on DHT

learn zinc PCA

Should zinc be taken orally or applied topically for better results in hair growth? Oral zinc supplementation is generally more effective for promoting hair growth than topical application.

learn retinol

How does retinol improve scalp health and prepare the skin for other hair growth treatments? Retinol improves scalp health by promoting cellular turnover and reducing congestion.

learn Hair Transplant

When will I see new hair growth after a hair transplant? New hair growth usually starts 2-4 months after a hair transplant.

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Clinics

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Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas