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5 / 57 resultslearn Valproic acid
an anticonvulsant repurposed for hair loss via histone inhibition
learn Stemoxydine
chemical from L'Oreal that encourages hair to enter growth phase
learn Rapamycin
mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth
learn Exosomes
Microscopic delivery system that sends growth-promoting signals to hair follicles
Research
5 / 1000+ results![Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls](/images/research/f85b2dbf-d3b1-4f7a-9572-f4c62edb6ee0/small/5485.jpg)
research Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research Decision letter for “Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls”
research Author response for “Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls”
research Decision letter for “Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls”
research Review for “Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls”
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5 / 1000+ resultscommunity Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.
A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.
community HairClone developing cell replacement treatments for Hair Loss
HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.
community HairClone: Good info from their site
HairClone aims to rejuvenate miniaturizing hair follicles through follicle banking and cell expansion, with treatments potentially available in the UK by 2022. The process involves extracting, storing, and cloning hair follicles, but full regenerative treatments will take many years to develop.
community Verteporfin and Microneedling
Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.
community Verteporfin with Microneedling (3mm-3.5mm): Bald to Full Head of Hair? Theory
The conversation is about using Verteporfin with microneedling as a potential hair loss treatment that may regenerate hair follicles with minimal scarring. There are concerns about the optimal dosage and the DHT sensitivity of the new follicles.