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HaCaT-Conditioned Medium Supplemented with Small Molecule Inhibitors SB431542 and CHIR99021 and Growth Factor PDGF-AA Prevents the Dedifferentiation of Dermal Papilla Cells In Vitro

research HaCaT-Conditioned Medium Supplemented with Small Molecule Inhibitors SB431542 and CHIR99021 and Growth Factor PDGF-AA Prevents the Dedifferentiation of Dermal Papilla Cells In Vitro

7 citations , March 2021 in “Molecular Medicine Reports”

A mix of specific inhibitors and a growth factor helps keep hair growth cells from losing their properties in the lab.

research Effect of Conditioned Media Collected from Human Amniotic Fluid-Derived Stem Cells on Skin Regeneration and Photo-Aging

9 citations , February 2014 in “Tissue Engineering and Regenerative Medicine”

Conditioned media from human amniotic fluid-derived stem cells helps skin heal and protects against aging from sun exposure.

research Monovalent Antibody-Conjugated Lipid-Polymer Nanohybrids for Active Targeting to Desmoglein 3 of Keratinocytes to Attenuate Psoriasiform Inflammation

18 citations , January 2021 in “Theranostics”

The targeted nanohybrids effectively reduced psoriasis symptoms and improved skin health.

Saponins of Korean Red Ginseng May Protect Human Skin from Adipokine-Associated Inflammation and Pigmentation Resulting from Particulate Matter Exposure

research Saponins of Korean Red Ginseng May Protect Human Skin from Adipokine-Associated Inflammation and Pigmentation Resulting from Particulate Matter Exposure

4 citations , February 2022 in “Nutrients”

Korean Red Ginseng saponins may protect skin from inflammation and darkening caused by air pollution.

research Pathophysiological Mechanisms of Hair Follicle Regeneration and Potential Therapeutic Strategies

June 2025 in “Stem Cell Research & Therapy”

Understanding hair growth pathways can lead to better hair loss treatments.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 40 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Minoxidil is a 5ar inhibitor according to research

in Research/Science 148 upvotes 1 month ago

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

community Wait, so retinol actually helps with hair growth? I heard it was the other way around a while ago and just accepted it..

in Treatment 6 upvotes 6 years ago

Retinol can help with hair growth, contrary to previous beliefs. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Anti-oxidants that reverse hairloss?

in Research/Science 89 upvotes 4 years ago

Resveratrol and fisetin, found in red wine and strawberries, may promote hair growth by affecting hair follicle cells. Users discuss various treatments, including natural remedies like saw palmetto and topical applications, with mixed opinions on their effectiveness compared to pharmaceuticals like finasteride.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 year ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

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