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GlossaryAntihistamines (H1 receptor antagonists)

medications that block histamine to relieve allergy symptoms

Antihistamines, also known as histamine blockers or H1 receptor antagonists, are medications that help alleviate allergy symptoms by blocking the action of histamine, a substance in the body that causes allergic reactions. They are commonly used to treat conditions such as hay fever, hives, and other allergic reactions, and can also be effective in managing symptoms of the common cold and motion sickness.

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Repurposing of H1-Receptor Antagonists Cetirizine, Loratadine, and Fexofenadine for Systematic Analysis of ClinicalTrials.gov Trials Using Semi-Automated Processes

research Repurposing of H1-Receptor Antagonists Cetirizine, Loratadine, and Fexofenadine for Systematic Analysis of ClinicalTrials.gov Trials Using Semi-Automated Processes

October 2023 in “Naunyn-Schmiedeberg's Archives of Pharmacology”

Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.

research FPRL1 Receptor Agonist Peptides Prevent Etoposide-Induced Alopecia in Neonatal Rats

8 citations , June 2004 in “Journal of Investigative Dermatology”

Certain peptides can prevent hair loss in young rats caused by a cancer drug.

research Application of Histamine Receptors H2R, H3R, and H4R, but Not H1R, in Dermatology

September 2014 in “International Journal of Dermatology and Venereology”

Certain histamine receptors (H2R, H3R, H4R) have unique roles in treating skin diseases, with H2R helping with chronic urticaria and other conditions, H3R providing pain relief and allergy benefits, and H4R reducing inflammation and itchiness.

research Clinical Snippets

June 2004 in “Journal of Investigative Dermatology”

Increased pigmentation may protect skin from UVB, new targets for skin disease treatments were identified, sunscreen ingredients don't affect hormones, TNF-α inhibitors may help diabetic wounds, and certain treatments could prevent chemotherapy-induced hair loss.

research Managing Hyperglycemia and Rash Associated With Alpelisib: Expert Consensus Recommendations Using the Delphi Technique

1 citations , January 2024 in “NPJ breast cancer”

Experts agree on how to manage sugar levels and skin reactions in patients taking the cancer drug alpelisib.

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community Earliest we can get legitimate pyrilutamide

in Research/Science 48 upvotes 3 years ago

Pyrilutamide, a drug in phase 3 trials in China, potentially becoming available in late 2023 or early 2024; Finasteride being used as a current treatment for hair loss; and the possibility of joining a group buy for black market versions of Pyrilutamide.

community Every research project and treatment hope is failing it‘s insane

in Treatment 15 upvotes 6 years ago

The conversation expresses frustration over the lack of progress in hair loss treatments, with specific mentions of Minoxidil, finasteride, and RU58841. Users discuss the slow development of new treatments and the potential of hair transplants.

community Winlevi coming out in 2019

14 upvotes 7 years ago

The conversation discusses the potential release of Winlevi in 2019 by Cassiopeia for hair loss treatment. It suggests a regimen combining minoxidil, Winlevi, Nizoral, and possibly dermarolling, with a comment mentioning Breezula as an alternative to finasteride without side effects.

community What do these pictures say about my hair and scalp if anything? Miniaturization, inflammation, etc.?

in Research/Science 74 upvotes 3 years ago

Hair loss and scalp issues, with people discussing possible treatments such as Nizoral shampoo, Minoxidil, neem oil, and finasteride.

community My dermatologist gave me free FIN!

in Finasteride/Dutasteride 307 upvotes 1 year ago

A user shared a positive experience about receiving free finasteride from their dermatologist. Others discussed the varying costs of finasteride in different countries.

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