March 2024 in “Nutrients” Gynostemma pentaphyllum and its component damulin B could help hair grow by activating certain cell pathways.
April 2016 in “Journal of Investigative Dermatology” Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.
April 2016 in “Journal of Investigative Dermatology” Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.
4 citations
,
February 2025 in “Nutrients” This randomized, double-blind, placebo-controlled clinical trial involving 100 adults assessed the efficacy and safety of Gynostemma pentaphyllum (GP) extract for hair health enhancement. Over 24 weeks, participants consuming GP extract experienced significant improvements in hair elasticity, density, and diameter compared to the placebo group, with a threefold increase in elasticity and density and a fourfold increase in diameter. Subjective satisfaction scores supported these findings, indicating reduced hair damage and dryness. No significant changes in hair glossiness were noted, and safety evaluations showed no severe adverse events, highlighting GP extract's potential as a safe and effective ingredient for hair care.
Male and female Gynostemma longipes plants have significant chemical differences.