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    GlossaryGlycogen Synthase Kinase-3 Inhibitor (GSK3 Inhibitor)

    compound that blocks the enzyme GSK-3, affecting cell processes

    A Glycogen Synthase Kinase-3 Inhibitor (GSK-3 Inhibitor) is a type of compound that blocks the activity of the enzyme glycogen synthase kinase-3 (GSK-3). This enzyme is involved in various cellular processes, including the regulation of glycogen metabolism, cell division, and signaling pathways. Inhibiting GSK-3 has potential therapeutic applications for conditions like Alzheimer's disease, diabetes, and certain types of cancer, as well as promoting hair growth in cases of alopecia.

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      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  50 upvotes 4 months ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community GT20029 and PP405 the new fin and min that we been waiting for ?

      in Chat  31 upvotes 2 weeks ago
      PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

      community Does melatonin dissolve in isopropyl alcohol

      in Technology  7 upvotes 2 years ago
      The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.