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Supplementary Material for: Dexamethasone, a Synthetic Glucocorticoid, Induces the Activity of Androgen Receptor in Human Dermal Papilla Cells

research Supplementary Material for: Dexamethasone, a Synthetic Glucocorticoid, Induces the Activity of Androgen Receptor in Human Dermal Papilla Cells

January 2022 in “Figshare”

Dexamethasone increases androgen receptor activity in scalp cells, which might explain stress-related hair loss.

research Glucocorticoid Receptor Antagonism Improves Glucose Metabolism in a Mouse Model of Polycystic Ovary Syndrome

December 2023 in “Journal of the Endocrine Society”

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

research Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An In Silico and In Vitro Study

29 citations, October 2020 in “Environmental health perspectives”

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

research The Role of Dexamethasone in Mediating the Contradictory Effects of Wnt Antagonists SFRP2 and SFRP3 on Human Hair Follicle Growth

October 2023 in “Scientific reports”

Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.

research Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology

176 citations, January 2003 in “Journal of Investigative Dermatology”

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

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community where does the renewed spironolactone hype come from?

in Research/Science 8 upvotes 2 years ago

Topical spironolactone is gaining attention as an alternative hair loss treatment, but it's not as effective as other options like finasteride. Oral spironolactone can cause side effects in men, and there are better topical alternatives like RU, Pyril, and CB.

community Sandalore: a scientific homemade approch

20 upvotes 6 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

in Research/Science 134 upvotes 9 months ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

community Lab results from actifolic RU58841

in Product 39 upvotes 1 year ago

The post discusses the user's experience with hair loss treatment RU58841, which was tested for quality and found to be 96+% pure. The conversation includes various responses, with some users questioning the safety of the product and others expressing satisfaction with the test results.

community I’ve been using min and nizoral for 7 years, losing a lot of hair in the meantime. Here’s what happened when I added 1mg fin daily and 1.5mm micro needling weekly.

in Progress Pictures 213 upvotes 2 years ago

The positive effects of Finasteride, a hair loss treatment; and various other treatments such as Minoxidil and Nizoral that can be used to treat hair loss. Additionally, other methods are discussed, such as micro needling and taking spearmint supplements, which have been seen to help in some cases.

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