July 2025 in “Frontiers in Pharmacology” This study highlights the potential of GPR30 and its selective agonists as promising therapeutic targets for treating hair loss disorders and conditions that respond to estrogen, emphasizing their role in modulating hair growth.
19 citations
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January 2015 in “Scientific Reports” This study found that the GPR39 receptor plays a novel role in accelerating wound healing in mouse skin, although it is not essential for skin development or homeostasis.
1 citations
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March 2023 in “Science Translational Medicine” The researchers reported that targeting glycoprotein 130's signaling site in animal models promoted tissue regeneration and reduced osteoarthritis progression through anti-inflammatory and protective effects.
March 2023 in “Biomedicine & Pharmacotherapy” This study found that GPR40 agonists may promote hair growth by inducing angiogenesis via specific molecular pathways in both cell and animal models, suggesting potential for hair loss treatment.
January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that inhibiting the gp130 Y814 signaling module promotes tissue regeneration and may prevent pathological outcomes after injury in animal models.