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research Gouty Alopecia: An Intriguing Manifestation of Disseminated Tophaceous Gout

January 2025 in “Journal of Skin and Stem Cell”

This case report describes a middle-aged man with chronic tophaceous gout who experienced a rare form of non-scarring alopecia due to urate crystal deposition around hair follicles, leading to hair loss that remarkably improved with targeted treatment including allopurinol and lifestyle changes.

research Сечова кислота в житті чоловіка

September 2024 in “The Scientific Issues of Ternopil Volodymyr Hnatiuk National Pedagogical University Series pedagogy”

This study reports that hyperuricemia is a widespread metabolic condition linked with several diseases, including gout and cardiovascular disease, and highlights the importance of lifestyle modifications, particularly in males, for managing this condition efficiently.

research Cutaneous manifestations of metabolic diseases: uncommon presentations

20 citations , September 2005 in “Clinics in Dermatology”

This review discusses the skin manifestations of metabolic diseases like diabetes and gout, emphasizing their role in diagnosis and monitoring, but it presents no new research findings.

research Perilla frutescens: A Rich Source of Pharmacological Active Compounds

21 citations , June 2022 in “Molecules”

This review discusses the phytochemistry and pharmacological activities of Perilla frutescens, detailing its bioactive compounds and their potential health benefits, but reports no new clinical results.

research Sanna Makki (Cassia angustifolia Vahl.): An Ancient Remedy in Modern Pharmacology: An Overview

October 2025 in “Journal of Drug Delivery and Therapeutics”

In this review, the researchers compared the traditional use of Senna Makki in Unani medicine for various ailments to modern pharmacological evidence, endorsing its role as a laxative but indicating further research is needed for its efficacy in other therapeutic areas.

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Clinics

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Learn

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Baricitinib

JAK inhibitor pill used for severe alopecia areata

Baricitinib: How did a drug for arthritis end up helping people regrow hair from alopecia areata? Baricitinib, an arthritis drug, was FDA-approved in 2022 for adults with severe alopecia areata after trials in which about a third of patients on 4 mg regained most scalp hair. It carries an FDA boxed warning, and regrowth is usually lost when it is stopped.

learn Tofacitinib

What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata? Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.

learn Ginkgo biloba

Is ginkgo biloba effective for all types of hair loss, including alopecia areata? No controlled human trial has tested ginkgo biloba for any type of hair loss, including alopecia areata; the only direct hair evidence is a 1993 mouse study. Ginkgo may increase bleeding risk with blood thinners.

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Community Join

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community Creatine? Experiences?What say YOU?

6 upvotes 6 months ago

Creatine may cause hair shedding in some individuals, but there is no strong scientific evidence linking it to hair loss. Many users report personal experiences of increased hair loss with creatine, while others see no effect; OP is considering creatine while using finasteride and topical minoxidil for hair loss.

community Rosemary oil's potency as a dht blocker

in Research/Science 65 upvotes 2 years ago

Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

413 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community can someone help me identify these pls

in Treatment 10 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community [Discussion] Trichoscopy in sudden-onset AGA: Pathology and reversibility of "Yellow Dots" without 5AR-inhibitors?

4 upvotes 6 months ago

Hair loss treatments discussed include microneedling, minoxidil, tretinoin, finasteride, dutasteride, pumpkin seeds, saw palmetto, and scalp massage. The consensus is that finasteride or dutasteride is necessary for significant regrowth, while other methods may only slow hair loss.

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