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    Did you mean Glycogen Synthase Kinase-3 Inhibitor?
    Glossary Glycogen Synthase Kinase-3 Inhibitor

    compound that blocks the enzyme GSK-3, affecting cell processes

    A Glycogen Synthase Kinase-3 Inhibitor (GSK-3 Inhibitor) is a type of compound that blocks the activity of the enzyme glycogen synthase kinase-3 (GSK-3). This enzyme is involved in various cellular processes, including the regulation of glycogen metabolism, cell division, and signaling pathways. Inhibiting GSK-3 has potential therapeutic applications for conditions like Alzheimer's disease, diabetes, and certain types of cancer, as well as promoting hair growth in cases of alopecia.

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    Research 10 of 769

    1. Discovery and Optimization of Novel Pyridines as Highly Potent and Selective Glycogen Synthase Kinase 3 Inhibitors 2019
    2. Influencing hair regrowth with EGCG by targeting glycogen synthase kinase-3β activity: a molecular dynamics study Journal of Receptors and Signal Transduction · 2025
    3. Sustained release of inhibitor from bionic scaffolds for wound healing and functional regeneration Biomaterials Science · 2020 · 8 citations
    4. Hair follicle stem cell differentiation is inhibited through cross‐talk between Wnt/β‐catenin and androgen signalling in dermal papilla cells from patients with androgenetic alopecia British Journal of Dermatology · 2012 · 95 citations
    5. Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection Cell Host & Microbe · 2016 · 133 citations
    6. Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells PLOS ONE · 2012 · 85 citations
    7. GSK-3 Inhibitors: Recent Developments and Therapeutic Potential Current signal transduction therapy · 2008 · 3 citations
    8. Human placental extract exerts hair growth-promoting effects through the GSK-3β signaling pathway in human dermal papilla cells International Journal of Molecular Medicine · 2015 · 20 citations
    9. Baicalin increases hair follicle development by increasing canonical Wnt/β‑catenin signaling and activating dermal papillar cells in mice International Journal of Molecular Medicine · 2018 · 23 citations
    10. Escin Activates Canonical Wnt/β-Catenin Signaling Pathway by Facilitating the Proteasomal Degradation of Glycogen Synthase Kinase-3β in Cultured Human Dermal Papilla Cells Current Issues in Molecular Biology · 2023
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