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Elucidating the Roles of Three β-Glucuronosyltransferases Acting on Arabinogalactan-Proteins Using a CRISPR-Cas9 Multiplexing Approach in Arabidopsis

research Elucidating the Roles of Three β-Glucuronosyltransferases Acting on Arabinogalactan-Proteins Using a CRISPR-Cas9 Multiplexing Approach in Arabidopsis

28 citations , May 2020 in “BMC plant biology”

The study concluded that three enzymes are important for plant development by affecting sugar composition and calcium binding in plants.

Physicochemical Properties of pH-Sensitive Hydrogels Based on Hydroxyethyl Cellulose–Hyaluronic Acid for Transdermal Delivery Systems for Skin Lesions

research Physicochemical Properties of pH-Sensitive Hydrogels Based on Hydroxyethyl Cellulose–Hyaluronic Acid for Transdermal Delivery Systems for Skin Lesions

118 citations , May 2015 in “European journal of pharmaceutics and biopharmaceutics”

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells

47 citations , March 2019 in “Journal of immunology research”

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

research A Review of the Cosmetic Use and Potentially Therapeutic Importance of Hyaluronic Acid

24 citations , July 2022 in “Journal of Applied Pharmaceutical Science”

Optimizing production conditions can improve hyaluronic acid's effectiveness and cost in cosmetics and therapy.

research The Role of Versican in the Skin Extracellular Matrix and Its Interaction with Hyaluronic Acid

2 citations , January 2019 in “Biomecánica”

Hyaluronic acid and versican are important for skin healing and hair growth and might help in regenerative medicine.

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community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 year ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community When you think about it blocking dht is not that big of a deal as it’s made out to be

in Research/Science 4 days ago

Reducing sebum can indirectly lower DHT levels, with treatments like accutane, tretinoin, and green tea extract acting as DHT blockers. Accutane can lower DHT levels by reducing 5α-reductase activity, but its impact on hair varies.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 195 upvotes 8 months ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community Minoxidil is highly toxic to pets — help push for proper labeling [Petition]

in Minoxidil 251 upvotes 6 months ago

Minoxidil is highly toxic to pets, particularly cats and dogs, and there is a call for proper labeling to warn pet owners. Despite some skepticism about the effectiveness of petitions, many agree that awareness and caution are necessary to prevent accidental poisoning.

community Why isn't anybody on topical bicalutamide?

in Research/Science 4 upvotes 1 year ago

Topical bicalutamide is discussed as a potential hair loss treatment. Other treatments mentioned include Minoxidil, finasteride, and RU58841.

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