research Uncomplicated differentiation of stem cells into bipolar neurons and myelinating glia
Hair follicles can be used to easily create neurons and glial cells for potential nerve repair.
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5 / 1000+ resultsresearch Differential expression levels of Sox9 in early neocortical radial glial cells regulate the decision between stem cell maintenance and differentiation
This study found that Sox9 plays a critical role in maintaining radial glial progenitor cells and regulates the timing of their generation of upper-layer cortical neurons.
research Combination of media, biomaterials and extracellular matrix proteins to enhance the differentiation of neural stem/precursor cells into neurons
This study observed that NSPC predominantly differentiated into neurons when exposed to serum fractions with molecules under 100 kDa, particularly with biomaterial and fibronectin, in the presence of basic fibroblast growth factor.
research Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells
In this study, dermal papilla cells from rat vibrissae showed potential for treating CNS injuries by secreting neurotrophic factors and promoting neuronal differentiation more effectively than bone marrow mesenchymal stem cells.
research Differentiation of nestin-negative human hair follicle outer root sheath cells into neurons in vitro
This study found that nestin-negative hair follicle stem cells can differentiate into neural stem cell-like cells, but not mature neurons, through a multi-step neuro-induction process.
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