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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

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      community Why is there so many people claiming Dutasteride destroyed their hair?

      in Chat  25 upvotes 10 months ago
      Some people claim Dutasteride worsened their hair loss, causing concern among users. Reasons suggested include initial shedding phases, incorrect attribution to Dutasteride when other factors are involved, genetic variations affecting drug response, and the possibility of non-authentic medication.

      community How do we only have two treatments to combat hair loss at this point in time?

      in Chat  211 upvotes 1 year ago
      The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

      community Painkillers May Block Minoxidil

      in Research/Science  15 upvotes 2 weeks ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community 1.5 Year - Bad Results (HT, FIN, MINO, PRP, etc)

      in Progress Pictures  63 upvotes 7 months ago
      A user shared their disappointing results after 1.5 years of hair treatments, including a hair transplant, finasteride, minoxidil, PRP, vegan shampoo, and more. They are considering switching to dutasteride, oral minoxidil, and improving their microneedling routine.