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research Fetal Programming of Polycystic Ovary Syndrome by Androgen Excess: Evidence from Experimental, Clinical, and Genetic Association Studies

253 citations , March 2006 in “The Journal of Clinical Endocrinology and Metabolism”

This review discusses the hypothesis that polycystic ovary syndrome may originate in fetal life due to prenatal androgen exposure, but reports no new clinical results.

research Coregulation of Genetic Programs by the Transcription Factors NFIB and STAT5

20 citations , March 2014 in “Molecular Endocrinology”

This study suggests that NFIB and STAT5 work together to control cell-specific genetic programs in mammalian tissues, particularly in mammary and hair follicle stem cells.

research Synthetically programmed antioxidant delivery by a domesticated skin commensal

8 citations , February 2025 in “Cell Systems”

This study developed a genetic toolbox to engineer Cutibacterium acnes for dermal applications, successfully creating a strain that secretes antioxidants to reduce oxidative stress in a UV stress model.

research Shortcutting the diagnostic odyssey: the multidisciplinary Program for Undiagnosed Rare Diseases in adults (UD-PrOZA)

8 citations , May 2022 in “Orphanet Journal of Rare Diseases”

This study reported that the Undiagnosed Disease Program at Ghent University Hospital successfully provided definite diagnoses for 18% of referred adults with suspected rare diseases, primarily through genomic technologies.

research P4 Outcome following switch between brand name and generic tacrolimus in paediatric population

3 citations , January 2018 in “Archives of Disease in Childhood”

In this study, researchers at Nottingham Children's Renal Unit found that most pediatric patients switching from Prograf to the generic tacrolimus preparation Adoport maintained stable tacrolimus levels and therapeutic effectiveness, supporting Adoport's use as a cost-saving alternative for the NHS.

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community Why do patients drop back to baseline/pre-treatment soon after quitting Finasteride?

in Research/Science 10 upvotes 10 months ago

Stopping finasteride often leads to rapid hair loss, returning to a genetic baseline, as the drug temporarily halts hair loss and promotes regrowth. The discussion explores the complexity of hair loss, suggesting that factors beyond DHT, such as genetics and scalp conditions, may play a role.

community Can hard water affect your scalp/hair?

14 upvotes 5 years ago

Hard water may contribute to an itchy, dry scalp and hair issues, but it doesn't affect genetic hair loss. Some users suggest using distilled water or a water softener to alleviate symptoms.

community How is this even possible that there is no cure till now

in Technology 155 upvotes 5 months ago

There is no permanent cure for hair loss; treatments like finasteride, minoxidil, and hair transplants require ongoing use and are not universally effective. Genetic complexity and financial incentives for ongoing treatments hinder the development of a definitive cure.

community Genomic Sequencing for Hair Loss

in Research/Science 156 upvotes 6 months ago

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

community Does dutasteride stop hair loss forever?

in Finasteride/Dutasteride 38 upvotes 1 year ago

Dutasteride and finasteride can significantly slow or halt hair loss, with some users experiencing regrowth, but results vary. Lifestyle factors and individual genetic predispositions also play a role in hair loss outcomes.

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