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research MendelVar: gene prioritization at GWAS loci using phenotypic enrichment of Mendelian disease genes

2 citations , April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

This article discusses the MendelVar webserver, which integrates Mendelian disease data with GWAS findings to prioritize candidate genes for complex traits and reports no new experimental results.

research Identifying critical cell types and gene regulatory pathways for hair and skin disease

July 2023 in “Nature Genetics”

Researchers identified key cell types and genes involved in hair and skin diseases.

research Association of insulin-like growth factor 2 Apa1 A820G gene (rs680) polymorphism with polycystic ovarian syndrome

January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology”

This study found that the IGF2 gene Apa1 A820G polymorphism is associated with an increased risk of developing PCOS in the studied population.

research Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias

22 citations , January 2018 in “Experimental Dermatology”

This article reviews insights into the pathogenesis of primary cicatricial alopecias, such as lichen planopilaris, provided by emerging technologies, but it does not report new clinical results.

research Recent advances in the genetics of alopecia areata

April 2023 in “Medizinische Genetik”

This review summarizes recent genetic findings in alopecia areata research and their implications for developing new treatments, without reporting new clinical results.

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community What do you think are the biggest reasons for the rise in male pattern hair loss over the last 100 years?

1 month ago

Hair loss is reportedly starting earlier in younger generations, with potential causes including prediabetes and decreased dietary minerals and vitamins. Minoxidil is mentioned as a treatment that supports capillary health and promotes hair growth.

community Hair Loss Causes Depression. Not Finasteride.

187 upvotes 7 months ago

Finasteride and Dutasteride do not cause depression or mood disorders; hair loss itself may be a more significant factor. Some users experience side effects from Finasteride, but it is generally well-tolerated.

community Male pattern baldness is not cosmetic.

224 upvotes 10 months ago

Male pattern baldness is linked to health risks and should be treated medically. Finasteride is effective and should be insurance-covered.

community Connection between finasteride and nafld?

in Research/Science 4 upvotes 2 years ago

Finasteride may affect liver function and cortisol levels, potentially linking it to non-alcoholic fatty liver disease (NAFLD). More research is needed to understand this connection fully.

community Rate my MPB Genetics: Can I run Primobolan/Masteron? (Detailed MyHeritage DNA Data Included)

in General 262 upvotes 6 months ago

The user is using testosterone and finasteride to prevent hair loss and is considering adding Primobolan or Masteron, which are DHT-derivatives. They are seeking advice on their genetic risk for male pattern baldness and whether they can safely use these compounds without significant hair loss.

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