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Research

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research Dermatological aspects of gender affirming medical treatment in transgender and gender diverse people: A systematic review

2 citations , July 2024 in “International Journal of Transgender Health”

This study reviewed literature on dermatological changes in transgender and gender diverse individuals during gender affirming medical transition, identifying risks like acne and hypertrophic scars, and provided tailored care recommendations for health professionals.

research Gender-Affirming Hormonal Treatment in Transgender People Assigned Female at Birth (AFAB)

January 2026 in “Endocrinology”

research Epigenetic Effects of Gender-Affirming Hormone Treatment: A Pilot Study of the ESR2 Promoter’s Methylation in AFAB People

9 citations , February 2022 in “Biomedicines”

This study suggests that testosterone therapy in AFAB individuals may modify the methylation of the ESR2 promoter, with changes influenced by factors like total testosterone levels and age.

research Evaluating the psychosocial impact of gender‐affirming dermatology treatments: A systematic review

January 2024 in “JEADV clinical practice”

This study reviewed research on the psychosocial effects of gender-affirming dermatology treatments in transgender populations, finding mostly positive associations but noting significant limitations and the need for more comprehensive studies to clearly understand these effects.

research Patient-reported outcomes, provider-reported outcomes, and physiologic parameters after gender-affirming hormone treatment in Canada: a systematic review

January 2025 in “HORMONES”

This systematic review reported positive outcomes with gender-affirming hormone therapy in Canada and emphasized the urgent need for standardized outcome measurement tools to enhance evidence-based practices.

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Learn

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learn Hair Transplant

Can a hair transplant be combined with other treatments? Clinics commonly say a transplant is combined with other treatments, most often minoxidil, finasteride or PRP, but the evidence behind each add-on differs. Some of the add-ons offered, such as stem-cell or exosome products, are not approved treatments for hair loss.
Does insurance cover hair transplants? Insurance usually doesn't cover hair transplants unless for specific medical conditions.

learn Clascoterone

Can I use clascoterone if I'm undergoing gender-affirming hormone therapy? No published clinical trial has tested clascoterone in people on gender-affirming hormone therapy, so its safety in that group is unknown. The FDA label reports low systemic exposure and no described effect on blood testosterone, but it also records HPA-axis suppression and raised potassium in a small minority of subjects.

learn Cyproterone

Is cyproterone safe to use during gender transition? Regulators and a large French cohort study link higher-dose, long-term cyproterone acetate to meningioma, and its label also lists liver-enzyme and mood effects — so it is not a drug anyone should call safe in the abstract, and its use in gender-affirming care is a prescriber's decision with monitoring.

Community Join

5 / 147 results

community I don’t understand this, is he equating taking Fin with being on HRT?

303 upvotes 1 year ago

The conversation is about using finasteride and testosterone replacement therapy (TRT) for hair loss and their role in gender-affirming care. It debates whether these treatments are considered hormone replacement therapy (HRT) and their implications for both cisgender and transgender individuals.

community 1 year of treatment + frontal transplant = life-changing results.

in Progress Pictures 718 upvotes 11 months ago

A 30-year-old shared their successful hair restoration journey using a combination of liposomal topical finasteride and minoxidil, vitamins, and a second hair transplant in Greece, resulting in life-changing improvements without side effects. The user emphasized the importance of proper research for hair transplant clinics and expressed gratitude for finding an effective treatment protocol.

community Testing Results for RU58841 from Multiple Vendors

in Treatments 233 upvotes 2 years ago

RU58841 powder from a lab supplier was tested at a free drug testing service. The discussion includes using Minoxidil and finasteride for hair loss treatment.

community ftm (21) with hairloss, advice would be great

8 upvotes 2 weeks ago

The conversation discusses hair loss treatments, specifically finasteride, for a 21-year-old FTM individual concerned about hairline recession. Users suggest finasteride and possibly topical minoxidil, while noting potential side effects like menstrual cycle return and brain fog.

community I think I was coping. Telling myself I'm Norwood 5, but it's 6-7. No hope, even with upcoming HRT progress.

in Transgender 9 upvotes 4 months ago

The conversation is about dealing with hair loss and exploring treatments like HRT, Minoxidil, and micro-needling. The user is considering wigs and possibly a hair transplant while expressing feelings of self-doubt and seeking support.

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Clinics

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Hair Transplant
Safe Rebirth – Gender Affirming SurgeriesBarcelona, Catalunya · ES

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