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    Did you mean G protein-coupled receptor?
    GlossaryG-protein coupled receptor

    cell surface receptor that transmits external signals inside cells

    A G-protein coupled receptor (GPCR) is a type of cell surface receptor that plays a crucial role in transmitting signals from outside the cell to the inside. When a molecule, such as a hormone or neurotransmitter, binds to a GPCR, it activates an associated G-protein, which then triggers various cellular responses. This mechanism is essential for many physiological processes, including sensory perception, immune response, and cell communication.

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      community Roughly 1.5 years progress. Dut, Fin, Minox, RU.

      in Progress Pictures  799 upvotes 2 years ago
      A user's progress with treatments for hair loss, including Dutasteride, Finasteride, Minoxidil, and RU. Other members of the conversation provided tips such as using Microneedling and Tretinoin to increase regrowth and wounding areas of the scalp that are thinning in order to fill them in.

      community It’s over. NOTHING has worked.

      in Chat  95 upvotes 1 year ago
      A user who has been trying various treatments for hair loss for four years, with no success. Suggestions include use of minoxidil, finasteride, RU58841, microneedling, supplements and multivitamins, lifestyle changes, scalp biopsy, and SMP.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 7 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 8 months ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.