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research Hair surface interactions against different chemical functional groups as a function of environment and hair condition

17 citations , January 2023 in “International Journal of Cosmetic Science”

In this study, hydrophobic interactions were found to primarily drive deposition on virgin hair, while electrostatic interactions were more significant for bleached hair, highlighting different target moieties for hair conditioning products.

research Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin

35 citations , January 2011 in “Journal of Biological Chemistry”

This study found that overexpression of sPLA2-X in mice was associated with alopecia and hair follicle abnormalities, highlighting its potential role in hair follicle homeostasis.

research Expression and Function of Group IIE Phospholipase A2 in Mouse Skin

26 citations , May 2016 in “Journal of biological chemistry/The Journal of biological chemistry”

This study found that mice lacking sPLA2-IIE had distinct skin abnormalities, particularly affecting hair follicles, highlighting the differing roles of sPLA2 isoforms in mouse skin.

research Influence of Surface Functional Groups on the Hair Growth-Promoting Activities of Nanochitins: An In Vitro Analysis

November 2025 in “Biomacromolecules”

This research found that four types of biocompatible nanochitin promoted hair growth in mice, with partially deacetylated and phosphoric acid hydrolyzed nanochitins showing the best results, while amphoteric nanochitin provided the most balanced overall effect.

research Group-ICA Model Order Highlights Patterns of Functional Brain Connectivity

109 citations , January 2011 in “Frontiers in Systems Neuroscience”

The researchers reported that differences in brain functional connectivity between unmedicated seasonal affective disorder patients and healthy controls vary with ICA model order, peaking in volume at model order 70.

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community The Placebo Group Has It Worse Than The Standard Prescription 0.5mg Group. -The fear is all in your head.

190 upvotes 11 months ago

Dutasteride at 0.5mg may have fewer sexual side effects than expected, with many side effects attributed to psychological factors (nocebo effect). The placebo group experienced more side effects, suggesting fear and anxiety might contribute to perceived side effects.

community Dutasteride and TRT study indicates improvement in aging male symptoms and no difference between placebo group and dutasteride group

in Finasteride/Dutasteride 45 upvotes 1 month ago

Dutasteride is recommended for men on testosterone replacement therapy (TRT) with DHT-sensitive hair, as it does not interfere with TRT's anabolic effects and may improve libido and aging male symptoms. Users report varying experiences with libido when switching from finasteride to dutasteride, with some noticing improvements and others experiencing fluctuations.

community Could male-pattern baldness have a secondary photobiological function? The Solar Window Hypothesis

11 upvotes 4 weeks ago

Male-pattern baldness might increase UVB exposure on the scalp, potentially affecting vitamin D and skeletal health. The hypothesis is debated, with some seeing it as a minor benefit in specific contexts.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 7 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community Finasteride - impact on Neurosteroids, which yes, \are important and not a garbage hormone

in Research/Science 163 upvotes 1 year ago

Finasteride may affect neurosteroids, impacting mood and sexual function, with varied user experiences. Some report side effects like depression and sexual dysfunction, while others find it effective for hair retention or prefer alternatives like Dutasteride or topical treatments.

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Learn

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learn Thymosin Beta 4

What is Thymosin Beta 4, and why is it being researched in relation to hair follicle function and regeneration? Thymosin Beta 4 is a peptide being researched for its potential to enhance hair follicle regeneration.

learn Epidermal Growth Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Glycerin

Does topical glycerin have any effect on hair thickness or follicle function? Topical glycerin primarily hydrates hair but does not increase thickness or follicle function.

learn Selenium

What is Selenium and why is it important for healthy hair and scalp function? Selenium is essential for hair health due to its antioxidant properties and role in thyroid function.

learn zinc PCA

Why is zinc important for preventing hair loss and supporting hair follicle function? Zinc is crucial for hair follicle health, supporting growth and repair processes.

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