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research In vivo expansion and regeneration of full‐thickness functional skin with an autologous homologous skin construct: Clinical proof of concept for chronic wound healing

38 citations , March 2019 in “International Wound Journal”

In this study, a new cell-tissue technology using a patient's own skin to create a full-thickness skin autograft successfully treated a chronic wound larger than 200 cm², achieving complete functional skin coverage within 12 weeks and maintaining results at a 6-month follow-up.

research Cell-Laden Gel Biomimetic Skin Promotes Full-Thickness Skin Wound Regeneration

March 2026 in “Gels”

In this study, the researchers developed a biomimetic multilayer composite scaffold combining a decellularized amniotic membrane, fibroblast-laden collagen gel, and epidermal stem cells, which healed full-thickness skin wounds more quickly and effectively by regenerating hair follicles without scarring compared to Moropicin ointment.

research Newborn infant skin gene expression: Remarkable differences versus adults

20 citations , October 2021 in “PLoS ONE”

This study found significant differences in gene expression between newborn and adult skin, with infant skin notably increasing processes related to ECM organization, cell adhesion, and collagen fibril organization.

research Reconstitution of full-thickness skin by microcolumn grafting

38 citations , June 2016 in “Journal of Tissue Engineering and Regenerative Medicine”

This study demonstrated that implanting μm-scale full-thickness columns of human skin tissue into immunodeficient mice restored key features of normal human skin, suggesting potential for human wound repair with minimal donor site morbidity.

research Multi-faceted enhancement of full-thickness skin wound healing by treatment with autologous micro skin tissue columns

14 citations , January 2021 in “Scientific Reports”

This study found that "micro skin tissue columns" improved wound healing by enhancing re-epithelialization, collagen deposition, dermal remodeling, and reducing inflammation without causing long-term donor site morbidity.

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community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 7 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community Duoxidil, Dutasteride and oral Minoxidil

in Minoxidil 89 upvotes 11 months ago

The conversation discusses hair regrowth treatments, specifically using a combination of oral and topical minoxidil, oral and topical dutasteride, and PRP. There is skepticism about the authenticity of the results, with some users questioning the changes in hair and skin appearance.

community Why not just take the drugs before hair loss?

in Chat 123 upvotes 6 months ago

Finasteride and dutasteride are discussed as preventative treatments for hair loss, with some advocating for early use and others concerned about side effects, especially before full maturity. Many regret not starting these treatments earlier due to their effectiveness in preventing or slowing hair loss.

community Guys, we finally have an alternative to finasteride

in Research/Science 263 upvotes 1 year ago

A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.

community Has Anyone Lost Morning Erections Due to Finasteride & Got Them Back?

in Chat 58 upvotes 1 year ago

Finasteride can cause sexual side effects like reduced libido and weaker erections, but experiences vary. Some users switch to dutasteride or topical treatments, while others stop finasteride to restore normal sexual function.

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