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GlossaryFrontal Fibrosing Alopecia

scarring hair loss at the front hairline, often in postmenopausal women

Frontal Fibrosing Alopecia (FFA) is a type of scarring hair loss that primarily affects postmenopausal women, though it can occur in men and younger women. It is characterized by a progressive recession of the frontal hairline and often includes loss of eyebrows and other body hair. The condition is thought to be an autoimmune disorder, where the body's immune system mistakenly attacks hair follicles, leading to inflammation and permanent hair loss.

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research The Frontal Fibrosing Alopecia Syndrome: How a Single Word Name Change Might Change So Much

April 2025 in “International Journal of Dermatology”

Renaming frontal fibrosing alopecia to a syndrome could improve diagnosis and treatment.

research Pathogenic Variants Affecting Peptidyl Arginine Deiminase 3 and Its Major Substrates Underlie Central Centrifugal Cicatricial Alopecia

November 2024 in “Journal of Investigative Dermatology”

Genetic changes in specific proteins contribute to hair loss in some women of African descent.

research Acne-Associated Syndromes: Models for Better Understanding of Acne Pathogenesis

January 2012 in “Yearbook of Dermatology and Dermatologic Surgery”

Studying acne-related syndromes helps us understand acne causes and can lead to new treatments.

research Update on Frontal Fibrosing Alopecia

2 citations , April 2017 in “Actas Dermo-Sifiliográficas”

Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.

research Frontal Fibrosing Alopecia: A Survey in 16 Patients

123 citations , August 2005 in “Journal of the European Academy of Dermatology and Venereology”

The study found that Frontal Fibrosing Alopecia affects a broader age range of women and early treatment can help stop hair loss.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 1 year ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community A Different Take on Curing MBP

15 upvotes 7 years ago

Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

community Male pattern baldness is not cosmetic.

in Chat 219 upvotes 3 months ago

Male pattern baldness is linked to health risks and should be treated medically. Finasteride is effective and should be insurance-covered.

community My Theory Of Androgenic Alopecia

in Research/Science 19 upvotes 3 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

View more "frontal fibrosing alopecia syndrome" in community →