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    Glossary Folliculin

    protein regulating cell growth and energy metabolism

    Folliculin, also known as FLCN, is a protein encoded by the FLCN gene. It plays a crucial role in regulating cell growth and energy metabolism. Mutations in the FLCN gene are associated with Birt-Hogg-Dubé syndrome, a condition that can lead to hair follicle tumors, lung cysts, and an increased risk of kidney cancer.

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    1. Follicusan
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    Research 10 of 1000+

    1. Folliculin encoded by the <i>BHD</i> gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling Proceedings of the National Academy of Sciences · 2006 · 475 citations
    2. Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion PloS one · 2012 · 72 citations
    3. Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis 2012 · 47 citations
    4. Folliculin Deficient Renal Cancer Cells Show Higher Radiosensitivity through Autophagic Cell Death 2014 · 4 citations
    5. Folliculin: A surprising molecular brake in the human hair follicle Journal of Investigative Dermatology · 2026
    6. Folliculitis decalvans including tufted folliculitis: clinical, histological and therapeutic findings British Journal of Dermatology · 1999 · 226 citations
    7. Action of isotretinoin in acne rosacea and gram-negative folliculitis Journal of The American Academy of Dermatology · 1982 · 175 citations
    8. Follicular and epidermal alterations in patients treated with ZD1839 (Iressa), an inhibitor of the epidermal growth factor receptor 2002 · 169 citations
    9. Folliculitis decalvans Dermatologic Therapy · 2008 · 112 citations
    10. Rapidly progressing mycosis fungoides presenting as follicular mucinosis Journal of the American Academy of Dermatology · 2000 · 76 citations
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    Community 10 of 76

    1. Black light diagnosis of folliculitis Reddit · 26 Jul 2026
    2. 7.5 Months on Min + Fin — Progress Pics + Questions (Crown, Temples, Folliculitis) Reddit · 13 Mar 2026
    3. What’s the connection between folliculitis and hair loss? Reddit · 8 Apr 2025
    4. Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc... Reddit · 18 Mar 2025
    5. Finally Scalp Folliculitis-Free after 2 Decades of Suffering Reddit · 6 Nov 2024
    6. Do the more newer gen topical retinoids e.g. tazarotene outperform tretinoin in inducing follicular sulfotransferase activity? Reddit · 29 Jul 2026
    7. Pelage Pharmaceuticals’ PP405 and its Impact on Follicular Regeneration to be Presented at the American Academy of Dermatology (AAD) Annual Meeting 2026 28th march Reddit · 26 Mar 2026
    8. Pelage Pharmaceuticals’ PP405 and its Impact on Follicular Regeneration to be Presented at the American Academy of Dermatology (AAD) Annual Meeting 2026 Reddit · 18 Mar 2026
    9. Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting Reddit · 25 Dec 2024
    10. Information regarding Follicusan DP? Reddit · 22 Oct 2023
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