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    GlossaryKeratotic Plugs (follicular plugs)

    small, hardened accumulations of keratin blocking hair follicles

    Keratotic plugs, also known as keratin plugs or follicular plugs, are small, hardened accumulations of keratin and dead skin cells that block hair follicles. These plugs can lead to conditions like keratosis pilaris, where the skin becomes rough and bumpy, often resembling goosebumps. They are commonly found on the upper arms, thighs, and buttocks, and can sometimes cause inflammation or irritation.

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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn GHK-Cu

      a copper peptide showing promise in both regrowth and reversing gray hair

      learn Caffeine

      the stimulant you know and love can be used topically to stimulate hair

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      community Progress with 6 Years fin and a FUT (2017 vs 2023)

      in Is this regrowth?  210 upvotes 1 year ago
      The post discusses a user's six-year progress with finasteride and a Follicular Unit Transplant (FUT) for hair loss. The user shared before and after photos in reverse order, leading to confusion, but overall, the community responded positively to the user's hair regrowth.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 2 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Just quit nicotine and caffeine

      in Treatment  21 upvotes 2 years ago
      The user has been using finasteride and oral minoxidil for hair loss but hasn't seen improvement and is quitting nicotine and caffeine to see if it helps. Some believe quitting nicotine improved their hair health due to better blood flow, while others are skeptical about the impact of blood flow on hair loss.