12 citations
,
August 2015 in “Plastic Surgery” This study found that botulinum toxin type A significantly reduced skin flap necrosis in rats exposed to cigarette smoke, suggesting it may help improve flap viability in smokers.
2 citations
,
November 2002 in “Dermatologic Surgery” This review discusses three surgical strategies for hair restoration, emphasizing that both scalp reduction and flap rotation have unique benefits such as significant hair density, despite grafting techniques being more widely used, and reports no new clinical results.
This study found that local heterologous leukocyte-rich platelet-rich plasma improved distal skin flap viability in rats by reducing necrosis compared to the control group.
January 2006 in “Chinese Journal of Aesthetic Medicine” This study found that exogenous zinc improved the viability of ultralong random skin flaps in Wistar rats by reducing oxidative damage and increasing protective protein levels.
March 1998 in “Dermatologic Surgery” In this study, miniflap scalp reconstruction with a staged scalp-lifting procedure showed excellent flap viability, acceptable scarring, and customizable hair direction, offering a preferred option for hair relocation in selected cases.