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This study found that botulinum toxin type A significantly reduced skin flap necrosis in rats exposed to cigarette smoke, suggesting it may help improve flap viability in smokers.

This review discusses three surgical strategies for hair restoration, emphasizing that both scalp reduction and flap rotation have unique benefits such as significant hair density, despite grafting techniques being more widely used, and reports no new clinical results.

This study found that local heterologous leukocyte-rich platelet-rich plasma improved distal skin flap viability in rats by reducing necrosis compared to the control group.

This study found that exogenous zinc improved the viability of ultralong random skin flaps in Wistar rats by reducing oxidative damage and increasing protective protein levels.

In this study, miniflap scalp reconstruction with a staged scalp-lifting procedure showed excellent flap viability, acceptable scarring, and customizable hair direction, offering a preferred option for hair relocation in selected cases.

This study found that prolonged topical application of minoxidil significantly increased skin flap survival in rats by promoting angiogenesis compared to shorter application or a saline control.

This study concluded that microsurgical reconstruction is a reliable method to achieve stable coverage of large, complex scalp defects, although cancer control rates were poor.

This review examines the physiology of skin flap necrosis and various substances studied to improve flap viability, noting that promising results are mostly from animal studies, with nitroglycerin already tested in humans.

This review discusses the surgical methods of hair restoration, highlighting the density benefits of scalp reduction and rotation, but reports no new clinical findings.

This review discusses the concept of drug repositioning and highlights fragmin and protamine as emerging biomaterials for tissue engineering and regenerative medicine, but it reports no new clinical results.

This review explores techniques for scalp reconstruction, focusing on local flap design and execution, without reporting new clinical findings.

This study found that adipose-derived stem cell-conditioned media improved skin flap survival following ischemia/reperfusion injury in mice by increasing cell proliferation and the number of hair follicles, mediated by IL-6.

Tanshinone IIA helps protect tissue from low oxygen damage by activating certain cell pathways.

This article discusses scalp reconstruction techniques using rotation flaps, with no new clinical results reported.

This study reports that a prototype device may accurately measure changes in hair quantity, diameter, and density in patients with balding by assessing the cross-sectional area of hair bundles.

This study found that topical minoxidil can be effective in preventing flap necrosis during latissimus dorsi flap reconstruction in patients who have undergone neoadjuvant chemoradiation.

This article reviews the current basic science of angiosome theory and flap delay, applying this knowledge to modern scalp flap procedures, without reporting any new clinical findings.

This study concluded that the inferiorly based nasolabial flap is an effective and reliable option for reconstructing oral cavity defects in patients with oral submucous fibrosis, achieving significant improvements in mouth opening without serious complications.

This article discusses surgical treatments for male pattern hair loss in black individuals, emphasizing the need for technique adjustments due to specific characteristics of black skin and hair, but reports no new clinical results.

This article discusses the temporo-parieto-occipital flap for scalp reconstruction and reports no new clinical results; the authors emphasize its specific reconstructive indications.

In this study, researchers developed a new variant of the Mercedes flap with releasing incisions for reconstructing medium-sized scalp defects, demonstrating complete defect closure without complications in three patients following a single operation with excellent aesthetic outcomes.

The researchers reported that nasolabial flaps were effective for reconstructing small to intermediate oral cavity defects in early oral cancer patients, with overall good cosmetic and functional outcomes despite some complications.

This review discusses current hair removal strategies in paramedian forehead flap reconstruction and reports no new clinical results; it offers recommendations to improve aesthetic outcomes by guiding timing and technique selection.

This study reports that using a combined approach of free osteoseptocutaneous fibula flap and temporal artery-based scalp flap provided satisfactory aesthetic and functional outcomes in reconstructing gunshot-inflicted composite mandibular defects in males.

This study found that a combination of azelaic acid, minoxidil, and caffeine significantly reduced skin flap necrosis in rats, likely by increasing nitric oxide content and iNOS expression, compared to individual treatments.

This study suggests that using growth factors and ADSC-conditioned medium can enhance keratinocyte viability and migration in epidermal transplantation, potentially improving chronic wound healing rates with a patient-dependent effect.

This study found that minoxidil pretreatment in rat skin flaps enhanced angiogenesis and increased flap survival compared to untreated flaps, but was less effective at reducing necrosis than surgical delay.

This article reviews the history, methods, and complications of tissue expansion and serial excision for scar revision in the head and neck, and reports no new findings.

In this study, mixing mouse epithelial and dermal cells was the most successful method for reconstituting hair follicles in mice, with the hair patch assay providing the quickest results.

This review discusses various surgical methods for treating baldness and reports no new results, focusing instead on the evolution and current roles of these techniques.