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GlossaryFibroblast Growth Factor Receptor 2 (FGFR2)

protein involved in cell growth and tissue repair

Fibroblast Growth Factor Receptor 2 (FGFR2) is a protein that plays a crucial role in cell growth, differentiation, and tissue repair. It is particularly important in the development of bones and skin, and mutations in the FGFR2 gene can lead to various developmental disorders and contribute to conditions like craniosynostosis and certain cancers.

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research The Role of Fibroblast Growth Factor Receptor 2b in Skin Homeostasis and Cancer Development

125 citations , February 2007 in “The EMBO Journal”

Fgfr2b helps maintain healthy skin and prevent cancer.

research Fibroblast Growth Factor-7 and Hair Biology: Bridging Basic Science and Therapeutic Applications

January 2026 in “Current Issues in Molecular Biology”

FGF-7 helps hair grow by activating hair follicles and is a promising target for hair loss treatments.

research Role of FGFR2-Signaling in the Pathogenesis of Acne

63 citations , May 2009 in “Dermato-endocrinology”

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne

65 citations , February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology”

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

research Acne Syndromes and Mosaicism

1 citations , November 2021 in “Biomedicines”

Understanding how acne develops in different diseases could lead to new treatments.

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