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GlossaryFibroblast Growth Factor Receptor 2 (FGFR2)

protein involved in cell growth and tissue repair

Fibroblast Growth Factor Receptor 2 (FGFR2) is a protein that plays a crucial role in cell growth, differentiation, and tissue repair. It is particularly important in the development of bones and skin, and mutations in the FGFR2 gene can lead to various developmental disorders and contribute to conditions like craniosynostosis and certain cancers.

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research Role of FGFR2-Signaling in the Pathogenesis of Acne

63 citations, May 2009 in “Dermato-endocrinology”

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

research Role of Insulin Resistance and Diet in Acne

39 citations, January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne

65 citations, February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology”

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

research Acne Syndromes and Mosaicism

1 citations, November 2021 in “Biomedicines”

Understanding how acne develops in different diseases could lead to new treatments.

research Hedgehog And Gli Signaling In Embryonic Mammary Gland Development

25 citations, May 2013 in “Journal of mammary gland biology and neoplasia”

Hedgehog signaling is crucial for mammary gland development over hair follicles.

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