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This paper discusses the hypothesis that anti-acne agents may work by reducing FGFR2 signaling, and emphasizes FGFR2's potential role in acne pathogenesis, but it reports no new experimental findings.

This review explores the role of FGFR2b-signaling in the pathogenesis of acne, highlighting its influence on sebaceous gland physiology and the effects of anti-acne agents like isotretinoin.

This study found that an SNP in the FGFR2 gene, rs4752566, was significantly associated with hair thickness in Asian populations, suggesting an effect on hair morphology through altered FGFR2 expression levels.

In this study, HA-P5, a nanoparticle derived from peptide and polysaccharide conjugation, effectively reduced acne lesions and sebum production by inhibiting specific receptors in cells, without triggering unfavorable reactions compared to a commercial inhibitor, highlighting HA-P5's potential as a novel acne treatment.

This study found that, in mice, different precursor populations give rise to Merkel cells in hairy versus glabrous skin, but their formation is controlled by a common genetic program involving FGFR2 signaling.

Fgfr2b helps maintain healthy skin and prevent cancer.

This article discusses the association of acne with various systemic diseases, emphasizing the role of androgen steroids, insulin resistance, and inflammation in acne pathogenesis, but it reports no new clinical results.

This article discusses the role of growth hormone, insulin, and IGF-1 in acne development and highlights how diet and syndromic evidence support their involvement, but presents no new clinical findings.

In this study, researchers found that ligand homodimerization controls the receptor binding specificity of the FGF9 subfamily, preventing off-target activation of FGFR "b" isoforms.

This study found that mice lacking CD61 had significantly shorter lower incisors compared to wild-type mice, suggesting CD61 is crucial for proper tooth growth and pre-ameloblast proliferation.

This review elaborates on the concept of cutaneous mosaicism and its link to acneiform conditions, but it reports no new clinical results.

This paper reviews the emerging role of FGF-7 signaling in hair regeneration, highlighting its potential as a target for new therapies despite limited clinical trial data.

This study found that downregulation of EGF and KGF signaling is necessary for hair follicle initiation in placodes, revealing a new role for KGF in hair follicle formation in mice.

This study reports that sebaceous glands can regenerate after injury through stem cell plasticity, with hair-follicle-derived stem cells replacing sebaceous gland progenitors and playing a crucial role in the regeneration process, which is dependent on FGFR2 signaling and aided by hair growth induction.

This study found that keloid tissues exhibit epithelial-mesenchymal transition-related changes and alterations in gene expression, implicating these processes in the pathogenesis of keloids.

This review discusses findings from genetic studies on acne, highlighting progress in understanding its molecular pathogenesis without reporting new clinical results.

The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.

In this study, researchers found that reducing FGF20 expression in dermal papilla cells of fine-wool sheep impedes the growth and differentiation of hair follicle stem cells, providing insights into wool trait improvement and regenerative medicine applications.

This study found that a specific fragment of AIMP1 secreted by hair follicle stem cells can stimulate dermal papilla cells and promote hair regrowth.

This study found that overexpressing FGF22 in dermal papilla cells enhanced hair follicle stem cell proliferation and viability, while its knockout reduced these attributes, indicating its role in hair follicle regeneration.

This study found that DNA methylation regulates hair follicle differentiation in cashmere goats by suppressing gene expression during induction and enhancing it during differentiation, with potential involvement of specific lncRNAs.

This study reports that a prototype device may accurately measure changes in hair quantity, diameter, and density in patients with balding by assessing the cross-sectional area of hair bundles.

This abstract reviews recent findings on genetic factors in acne, highlighting the potential of genetic studies to advance understanding of its pathogenesis, but reports no new clinical results.

This study found that the bioconjugate nanoparticle HA-P5 significantly alleviated acne and reduced sebum production by inhibiting key signaling pathways without inducing unwanted protein expression that hinders acne treatment.

In this study, researchers reported that a keratinocyte growth factor-Ig fusion protein could specifically detect and localize KGFRs in epithelial tissues, suggesting a method for histochemical detection of growth factor receptors.

This study identified 96 cases of pilomatricomas linked to genetic syndromes, including a novel association with Apert syndrome, highlighting that these tumors often manifest as the first indication of underlying conditions in pediatric patients.

Researchers found an RNA transcript that might help control a growth factor linked to tumor development.

This review examines the roles of Hedgehog and Gli proteins in mouse embryonic mammary development and suggests that Gli3-repressor-mediated off-state of Hedgehog signaling determines mammary fate over hair follicle fate.

This review discusses the role of signaling networks in sebaceous gland development and disorders, highlighting recent insights from mouse models and cell line studies, but reports no new experimental results.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.