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research Mechanisms that regulate androgen receptor transcriptional activity

August 2019 in “Carolina Digital Repository (University of North Carolina at Chapel Hill)”

This study indicates that MAGE-11 modulates androgen receptor transcriptional activity through F-box interactions, independent of the activation function 2 pathway, revealing a novel mechanism for androgen receptor regulation.

research Skin expression of mammalian target of rapamycin and forkhead box transcription factor O1, and serum insulin‐like growth factor‐1 in patients with acne vulgaris and their relationship with diet

93 citations , January 2016 in “British Journal of Dermatology”

This study found that patients with acne vulgaris had higher serum IGF-1 levels and more intense FoxO1 and mTOR expression than controls, suggesting their role in acne pathogenesis.

research Identification and dissection of an enhancer controlling epithelial gene expression in skin

29 citations , February 2001 in “Proceedings of the National Academy of Sciences”

This study found that the HS III element in the K14 gene's regulatory sequence promotes gene expression in inner root sheath keratinocytes, highlighting cooperative interactions in keratinocyte-specific gene regulation.

research Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders

20 citations , December 2020 in “Frontiers in Immunology”

This study found that certain T cell-associated genes were upregulated in dogs with Vogt-Koyanagi-Harada syndrome and vitiligo, suggesting a shared immunopathogenesis with humans.

research RAGE and Its Ligands in Melanoma

1 citations , April 2015 in “InTech eBooks”

RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.

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community I'm quitting finasteride after almost 3 years of daily use

in Finasteride/Dutasteride 166 upvotes 11 months ago

A 23-year-old stopped using finasteride due to sexual side effects after three years. The discussion covers experiences with finasteride, dutasteride, and other treatments, noting varied side effects and effectiveness.

community Reversed my hairloss without fin/min. 2023 December to 2025 April. IDK what happened.

565 upvotes 1 year ago

A user reversed hair loss using 10% sulfur soap, which reduced scalp inflammation and possibly demodex mites. The user did not use finasteride or minoxidil, suggesting inflammation may contribute to hair loss.

community Roomate found my meds and made fun of me

in Chat 351 upvotes 1 year ago

A college student is embarrassed after their roommate found and mocked their hair loss medications, including Minoxidil and finasteride. The student is advised to report the privacy violation and consider finding a new roommate.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

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SMP Specialist
Corey Box
Melbourne, VIC, Australia
1+ yrs

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