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Tumor Necrosis Factor Alpha, Interferon Gamma, and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin

research Tumor Necrosis Factor Alpha, Interferon Gamma, and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin

24 citations , April 2013 in “PLOS ONE”

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

research Prolactin and the Skin: A Dermatological Perspective on an Ancient Pleiotropic Peptide Hormone

98 citations , December 2008 in “Journal of Investigative Dermatology”

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

research Prolactin: An Emerging Force Along the Cutaneous–Endocrine Axis

51 citations , July 2010 in “Trends in Endocrinology and Metabolism”

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

research The Prolactin Receptor as a Therapeutic Target in Human Diseases: Exploring New Potential Indications

38 citations , June 2015 in “Expert Opinion on Therapeutic Targets”

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

research Mind the Gender Gap: Does Prolactin Exert Gender and Site-Specific Effects on the Human Hair Follicle?

36 citations , November 2009 in “Journal of Investigative Dermatology”

Prolactin may affect hair growth differently based on gender and scalp area.

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community Why HMI115 should work if it doesn’t affect dht?

in Research/Science 16 upvotes 2 years ago

Hair growth can be induced without stopping DHT, as seen with Minoxidil. HMI115 may work by promoting follicle growth, not targeting the root cause of hair loss (DHT).