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      learn Mesotherapy

      technique to inject very small amounts of beneficial chemicals into the scalp

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      compound from cruciferous vegetables has some mild effects on DHT

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      natural substance from Neem tree with medicinal and pesticidal properties

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      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      by nkrata in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community [23M] 1.5 year update. Minoxidil+derma roller+hair oil

      in Progress Pictures  13 upvotes 1 year ago
      A user shared their 1.5-year experience using Minoxidil, a derma roller, and hair oil for hair loss, noting significant improvements in hair health and density. They also emphasized the importance of a healthier lifestyle and the positive impact of using a product combining Minoxidil with plant extracts.

      community Is trichosol meant to smell like ginger beer?

      in Minoxidil  5 upvotes 2 years ago
      A user is using a trichosol-based minoxidil solution to avoid scalp irritation and is asking if it should smell like ginger beer. They like the scent and want to confirm they have the correct product.

      community How to make topical finasteride?

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      The conversation is about making a topical finasteride solution by dissolving crushed finasteride tablets in an alcohol-based hair treatment. Ingredients of the hair treatment include alcohol, water, and various plant extracts and preservatives.