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community Veradermics VDPHL01 Topline Results for Extended-Release Oral Minoxidil

75 upvotes 5 months ago

Extended-release oral minoxidil (VDPHL01) shows promising results for hair growth with improved safety, achieving significant hair count increases and minimal side effects compared to placebo. The treatment is designed to maintain effective concentrations while reducing side effects, making it a safer option for those who cannot tolerate standard minoxidil.

community Following the recent IPO and the positive Phase 3 clinical data for VDPHL01 (extended-release oral minoxidil), what is the projected timeline for the FDA submission and the subsequent commercial availability on the market?

in Chat 4 upvotes 4 months ago

Veradermics' extended-release oral minoxidil is expected to be commercially available in 2027-2028, while another company, Minx, may release a similar product sooner. VDPHL01 is considered more clinically validated compared to Minx.

community Veradermics VDPHL01 Topline Results for Extended-Release Oral Minoxidil

in Minoxidil 11 upvotes 5 months ago

Veradermics is working on FDA approval for extended-release oral Minoxidil. Approval is expected around 2027.

community A minoxidil pill just posted strong phase 3 results. Up to 86% of men improved coverage in six months.

345 upvotes 2 months ago

VDPHL01, an extended-release oral minoxidil tablet, showed promising results in improving hair coverage for 79 to 86% of men in a trial, with fewer side effects compared to standard doses. Many users prefer oral minoxidil over topical due to ease of use and fewer side effects, especially for those with pets.

community 30 new hair per cm by extended release minoxidil

in Minoxidil 140 upvotes 5 months ago

Extended-release minoxidil shows promise for hair regrowth, potentially adding 30 new hairs per cm, but concerns about side effects like increased body hair and shortness of breath remain. Users discuss combining it with finasteride or dutasteride for better results, while some express skepticism about it being a complete cure.

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Research

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research 76221 Faster Onset and Superior Efficacy of an Investigational Extended-Release Oral Minoxidil Tablet (VDPHL01) Versus Topical and Immediate-Release Oral Minoxidil for Androgenetic Alopecia: Results from a Blinded Retrospective Investigator Global Assessment

July 2026 in “Journal of the American Academy of Dermatology”

research Three months extended-release microspheres prepared by multi-microchannel microfluidics in beagle dog models

6 citations , August 2021 in “International Journal of Pharmaceutics”

This study demonstrated that finasteride-loaded PLGA microspheres created using a novel microfluidic device exhibit extended drug release in beagle dogs, with modifications allowing for release up to 3 months.

research Effect of metformin by employing 2-hour postload insulin for measuring insulin resistance in Taiwanese women with polycystic ovary syndrome

6 citations , April 2016 in “Journal of the Formosan Medical Association”

This study found that metformin treatment improved clinical outcomes in Taiwanese women with polycystic ovary syndrome, notably in overweight and insulin-resistant patients.

research A 6-month prospective study on efficacy safety and QOL profiles of extended-release formulation of valproate in patients with epilepsy

13 citations , October 2010 in “Seizure”

This study reported that extended-release valproate significantly reduced seizure frequency and improved quality of life in epilepsy patients over six months, despite some adverse effects like weight gain and tremor.

research Combination tofacitinib and oral minoxidil treatment for severe alopecia areata

23 citations , September 2019 in “Journal of The American Academy of Dermatology”

In this retrospective analysis, combination therapy with tofacitinib and oral minoxidil led to significant scalp hair regrowth in patients with severe alopecia areata, with 67% achieving at least 75% regrowth, although the small sample size limits the findings.

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learn Minoxidil

Vasodilator used on the scalp and, at low doses, as a tablet

From hypertension to hair: the unexpected story of minoxidil Minoxidil was developed as an oral blood-pressure drug and approved as Loniten in 1979; unwanted hair growth in patients led to topical Rogaine, approved for men in 1988 and for women in 1991. Trials support topical minoxidil for pattern hair loss, while low-dose oral minoxidil is a prescription drug used off-label and needs medical supervision.
Minoxidil 2%, 5% and 10% which is better to use? In a randomized trial in men, 5% topical minoxidil produced more hair growth than 2%, and in one small trial 10% did not beat 5% and caused more irritation. No 10% product is approved in the US, and approved strengths differ by sex, so check the label for your product.
Minoxidil: the application and its effects counted in months Some people notice a temporary increase in shedding when they start; the US over-the-counter label says results may take 2 to 4 months, and trials measured results at around 4 months to a year.
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learn Nanoxidil

learn Redensyl

Cosmetic ingredient blend sold for thinning hair

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