Prepare to be disappointed by PP405 2/10/2026
Delayed release oral minoxidil is seen as a promising advancement for hair loss treatment, offering safer, higher doses and more consistent hair follicle stimulation compared to current options. However, it is not expected to replace finasteride or dutasteride, as it does not prevent androgenetic alopecia.
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5 / 5 resultscommunity On Fin 5 days a week and dut twice a week and still rapidly losing hair. HOW?? 9 months on fin!
A user using finasteride and dutasteride to treat hair loss, but still losing hair rapidly after stopping minoxidil. Replies suggest that the user should try oral minoxidil or switch to dutasteride for better results.
community Are these new hair loss treatments ever gonna release?
Hair loss treatments like Breezula and PP405 are delayed, with approvals taking years, while existing treatments like minoxidil and finasteride remain popular. New treatments like Clascoterone and Veradermics are in trials, but high costs and lengthy approval processes slow their release.
community I’m taking Veradermics VDPHL01 - AMA
A participant using Veradermics VDPHL01, an extended-release oral minoxidil, experienced significant hair regrowth from Norwood 6 to Norwood 3V without side effects. They plan to use dutasteride after the treatment to maintain results.
community PSA: You guys are paying way too much for your Finasteride and Minoxidil. Here's the cheapest I've found.
Finasteride and minoxidil can be obtained cheaply through Mark Cuban's Cost Plus Drugs and Costco's Kirkland brand, respectively, costing about $7.53/month combined. Amazon's RXPass and virtual visits at Dr. B. offer additional savings.
community Did Scientists Just Cure Baldness? UCLA’s New Molecule Could Revolutionize Hair Growth
PP405 shows promise for hair growth but may need continuous use like Minoxidil. Current treatments include Minoxidil, finasteride, and dutasteride, with skepticism about a true cure due to financial interests.
Related Research
6 / 6 results
research Primary cicatricial alopecia
This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.
research Recent Advances in Understanding of the Etiopathogenesis, Diagnosis, and Management of Hair Loss Diseases
This review article reports recent advancements in understanding, diagnosing, and treating various hair loss conditions, like androgenetic alopecia and alopecia areata, including their genetic factors and new therapeutic options, while also examining the impact of COVID-19 on hair loss.
research Androgenetic Alopecia: a Review and Emerging Treatments
This review covers the pathogenesis, diagnosis, and potential new treatments for androgenetic alopecia but reports no new clinical findings, highlighting an ongoing need for effective therapies.
research Androgenetic Alopecia
This review covers androgenetic alopecia's epidemiology, pathogenesis, current management options, and research trends, concluding that no definitive cure exists despite extensive interest and ongoing genetic research efforts.
research CXCL12 Neutralizing Antibody Promotes Hair Growth in Androgenic Alopecia and Alopecia Areata
This study found that subcutaneous injection of a CXCL12 neutralizing antibody significantly promoted hair growth in androgenic alopecia and inhibited hair loss in alopecia areata in mouse models, suggesting its potential as a promising treatment for hair loss.
research Minoxidil: a comprehensive review
This study reported that while topical minoxidil exhibits hair regrowth in androgenetic alopecia, oral minoxidil 5 mg/day was more effective than topical forms after six months, with low doses also potentially effective for women and other hair loss types.