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community 30 new hair per cm by extended release minoxidil

in Minoxidil 140 upvotes 4 months ago

Extended-release minoxidil shows promise for hair regrowth, potentially adding 30 new hairs per cm, but concerns about side effects like increased body hair and shortness of breath remain. Users discuss combining it with finasteride or dutasteride for better results, while some express skepticism about it being a complete cure.

community Veradermics VDPHL01 Topline Results for Extended-Release Oral Minoxidil

75 upvotes 4 months ago

Extended-release oral minoxidil (VDPHL01) shows promising results for hair growth with improved safety, achieving significant hair count increases and minimal side effects compared to placebo. The treatment is designed to maintain effective concentrations while reducing side effects, making it a safer option for those who cannot tolerate standard minoxidil.

community Following the recent IPO and the positive Phase 3 clinical data for VDPHL01 (extended-release oral minoxidil), what is the projected timeline for the FDA submission and the subsequent commercial availability on the market?

in Chat 4 upvotes 4 months ago

Veradermics' extended-release oral minoxidil is expected to be commercially available in 2027-2028, while another company, Minx, may release a similar product sooner. VDPHL01 is considered more clinically validated compared to Minx.

community Veradermics VDPHL01 Topline Results for Extended-Release Oral Minoxidil

in Minoxidil 11 upvotes 4 months ago

Veradermics is working on FDA approval for extended-release oral Minoxidil. Approval is expected around 2027.

community A minoxidil pill just posted strong phase 3 results. Up to 86% of men improved coverage in six months.

345 upvotes 1 month ago

VDPHL01, an extended-release oral minoxidil tablet, showed promising results in improving hair coverage for 79 to 86% of men in a trial, with fewer side effects compared to standard doses. Many users prefer oral minoxidil over topical due to ease of use and fewer side effects, especially for those with pets.

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Research

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research 76221 Faster Onset and Superior Efficacy of an Investigational Extended-Release Oral Minoxidil Tablet (VDPHL01) Versus Topical and Immediate-Release Oral Minoxidil for Androgenetic Alopecia: Results from a Blinded Retrospective Investigator Global Assessment

July 2026 in “Journal of the American Academy of Dermatology”

research A Review on an Evaluation of a Liposomal Hydrogel for Combined Minoxidil and Tretinoin Delivery in Androgenetic Alopecia

January 2025 in “International journal of research and scientific innovation”

This critique of a 2019 study highlights the potential of a liposomal hydrogel for delivering Minoxidil and Tretinoin to treat androgenetic alopecia, but underscores the need for in vivo trials and further stability and interaction analysis to validate its promise.

Designing, Optimizing, and Assessing a Novel Emulgel Containing Minoxidil for Controlled Drug Release Using Marine-Based Polymers

research Designing, Optimising, and Assessing a Novel Emulgel Containing Minoxidil for Controlled Drug Release, Incorporating Marine-based Polymers

February 2024 in “Current Drug Delivery”

In this study, researchers developed an emulgel formulation containing minoxidil for hair growth, using chitosan and fucoidan as gelling agents, achieving controlled drug release with 99.7% released by the 12th hour.

research ANDROGENETIC ALOPECIA: FROM MOLECULAR MECHANISMS TO ADVANCED TOPICAL DELIVERY SYSTEMS WITH EMPHASIS ON POLYMERIC MICELLES

June 2026 in “International Journal of Drug Delivery Technology”

This study highlights the potential of polymeric micelles in enhancing the targeted delivery and efficacy of treatments for androgenetic alopecia, by offering improved retention on the scalp, extended release, and reduced systemic side effects compared to conventional therapies like minoxidil and finasteride.

research Multistage Transdermal Nitric Oxide Delivery System for the Efficient Treatment of Androgenic Alopecia

November 2024 in “ACS Materials Letters”

This study developed a nitric oxide delivery system using PVA films and HA liposomes, which enhanced hair follicle vitality and repaired blood vessels in androgenic alopecia by promoting angiogenesis and reducing inflammation through the HIF-1 signaling pathway.

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learn Minoxidil

An essential vasodilator with some anti-androgenic effects

Minoxidil 2%, 5% and 10% which is better to use? In a randomized trial in men, 5% topical minoxidil produced more hair growth than 2%. There is no approved 10% product and no head-to-head trial showing it beats 5%; higher strengths mainly add irritation and systemic absorption. Approved strengths differ by sex, so check the label for your product.
Minoxidil: the application and its effects counted in months Expect initial shedding in the first month, with visible results typically by three to six months.
From hypertension to hair: the unexpected story of minoxidil Minoxidil was developed as an oral blood-pressure drug and approved as Loniten in 1979; unwanted hair growth in patients led to topical Rogaine, approved for men in 1988 and for women in 1991. Trials support topical minoxidil for pattern hair loss, while low-dose oral minoxidil is a prescription drug used off-label and needs medical supervision.
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learn Nanoxidil

Key Differences between minoxidil and nanoxidil? Nanoxidil has a lower molecular weight than minoxidil, enhancing absorption and reducing side effects.

learn Tretinoin

the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

learn Latanoprost

glaucoma medication with hair follicle stimulant effects

learn Redensyl

commercial product with a blend of mostly natural ingredients for hair regrowth

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