research Do we need hair follicle stem cells and hair follicle neogenesis to cure common hair loss disorders?
This document includes a brief professional profile of Dr. Ralf Paus but presents no research findings or study results.
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5 / 735 resultsresearch Protease activity, localization and inhibition in the human hair follicle
This study found that a combination of Trichogen and climbazole may inhibit protease activity and increase the force required to remove human hair, suggesting potential to reduce excessive hair shedding.
research Inhibition of 5α-Reductase, IL-6 Secretion, and Oxidation Process of Equisetum debile Roxb. ex Vaucher Extract as Functional Food and Nutraceuticals Ingredients
This study observed that the ethyl acetate extract of Equisetum debile showed high activity against 5α-reductase and lipid peroxidation with no cytotoxicity on dermal papilla cells.
research The Aromatase Inhibitor Fadrozole and the 5-Reductase Inhibitor Finasteride Affect Gonadal Differentiation and Gene Expression in the Frog Silurana tropicalis
This study found that chronic exposure to fadrozole or finasteride during frog development induced intersex individuals, which displayed different gene expression profiles depending on the chemical used.
research Exogen, Shedding Phase of the Hair Growth Cycle: Characterization of a Mouse Model
This study identified a distinct "exogen" phase in the hair cycle during which hair shedding occurs, primarily coupled with the anagen phase, rather than as part of the telogen phase.
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5 / 30 resultscommunity FINALLY stopped shedding constantly after 1 year on 5ar inhibitors!! Moral of the story: Just wait
After using finasteride for 7 months and dutasteride for 5 months, the user experienced a significant reduction in hair shedding and scalp itchiness. They advise patience with hair loss treatments and suggest focusing on a good haircut and reducing stress.
community Does this look like new growth ? Dut .5 since May 15th
The user switched from finasteride to Dutasteride 0.5 mg since mid-May and is experiencing shedding but noticing baby hairs, questioning if they are new growth. Consistency with Dutasteride and Minoxidil is advised for better results, with improvements expected after the initial shedding phase.
community Summary of Procapil video by Haircafe
Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.
community Another anecdotal claim DUT can make things worse than FIN - with pictures
The user experienced initial hair improvement with finasteride but noticed worsening hair loss after switching to dutasteride. They are considering returning to finasteride due to persistent hair shedding and scalp itch.
community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism
Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.
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