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      Copper Deficiency: A New Reason for Androgenetic Alopecia?

      research Copper Deficiency a New Reason of Androgenetic Alopecia?

      3 citations , May 2014 in “InTech eBooks”
      This review discusses the genetic and androgen-related factors in androgenetic alopecia, highlighting a specific polymorphism in the AR protein associated with male pattern hair loss, and reports no new clinical results.
      5-Alpha Reductase Deficiency

      research 5-Alpha reductase deficiency

      38 citations , October 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity”
      This review discusses the clinical and molecular history of 5-alpha reductase deficiency, highlighting its role in male sexual differentiation and potential therapeutic applications, but reports no new research outcomes.
      The Hormonal Background of Hair Loss in Non-Scarring Alopecias

      research The Hormonal Background of Hair Loss in Non-Scarring Alopecias

      February 2024 in “Biomedicines”
      This review examines the hormonal causes of hair loss, noting how androgen excess can lead to follicle miniaturization and linking estrogen deficiency and thyroid dysfunction to common alopecia types. It further discusses hormonal treatments such as finasteride, dutasteride, and spironolactone.
      Commonly Prescribed Medications Associated With Alopecia

      research Commonly prescribed medications associated with alopecia

      August 2023 in “Journal of The American Academy of Dermatology”
      In this commentary, the authors highlighted that valproic acid, unlike lamotrigine, is notably associated with alopecia in various studies, with an incidence rate up to 12% and mechanisms involving telogen effluvium and hyperandrogenism contributing to hair loss in patients.

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      community 25 years on Finasteride and it's not working anymore.

       324 upvotes 6 months ago
      A 47-year-old has been using finasteride for 25 years for hair loss, but it's less effective now. Suggestions include switching to dutasteride, stopping anastrozole, and trying minoxidil, microneedling, and possibly TRT.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 2 years ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

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