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GlossaryEstrogen Receptor Beta (ERB)

protein that binds estrogen and influences various biological processes

Estrogen Receptor Beta (ERβ) is one of the two main types of receptors that bind to the hormone estrogen, the other being Estrogen Receptor Alpha (ERα). ERβ is involved in regulating various biological processes, including reproductive functions, bone density, and even hair growth. It plays a crucial role in mediating the effects of estrogen in different tissues, and its activity can influence conditions like alopecia, where hair loss occurs.

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research Dermatologic Adverse Events Associated With Afatinib: An Oral ErbB Family Blocker

87 citations , March 2013 in “Expert Review of Anticancer Therapy”

Afatinib often causes skin problems that need proactive management.

research Targeted Expression of Activated ErbB-2 to the Epidermis of Transgenic Mice Elicits Striking Developmental Abnormalities in the Epidermis and Hair Follicles

35 citations , April 1998 in “PubMed”

Activated erbB-2 in mice skin causes severe skin and hair abnormalities.

research Erbium-Yttrium-Aluminum-Garnet Laser Irradiation Ameliorates Skin Permeation and Follicular Delivery of Antialopecia Drugs

31 citations , September 2014 in “Journal of Pharmaceutical Sciences”

Using a special laser can improve how well hair loss treatments get into the skin and hair follicles.

research Effects of Non-Ablative Fractional Erbium Glass Laser Treatment on Gene Regulation in Human Three-Dimensional Skin Models

24 citations , January 2016 in “Lasers in Medical Science”

Erbium glass laser treatment may help with skin remodeling, reduce inflammation, and improve skin cell maturation.

research Cutaneous Lesions in Rats Following Administration of an Irreversible Inhibitor of ErbB Receptors, Including the Epidermal Growth Factor Receptor

21 citations , April 2008 in “Toxicologic Pathology”

CI-1033 causes skin lesions in rats, similar to humans, due to EGF receptor inhibition.

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community Starting Way-316606 for the first time today.

in Research/Science 30 upvotes 9 months ago

A user is experimenting with a homemade solution of WAY-316606 for hair regrowth, combining it with other treatments like minoxidil and dutasteride. The community expresses concern over the safety and mental health implications of such drastic measures, with mixed opinions on the effectiveness of WAY-316606.

community Hair energiser tablets, useful or not?

in Product 1 year ago

A user is unsure if "Hair Energiser" tablets are effective for hair growth after a year of use. Replies suggest using finasteride instead and call the tablets a scam.

community Why is the general consensus that if you can’t tolerate 5AR Inhibitors you’re “cooked”?

in Research/Science 13 upvotes 2 months ago

Alternatives to finasteride for hair loss include minoxidil, alfatrodial, fluridil, pyrilutamide, and Nizoral. These treatments may not be as effective as finasteride but can help slow hair loss progression.

community The mechanism of androgenic alopecia

in Research/Science 35 upvotes 2 months ago

DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

in Update 34 upvotes 6 years ago

The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

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