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GlossaryEnzalutamide

blocks male hormones to treat prostate cancer

Enzalutamide, also known by the brand name Xtandi, is a medication used to treat prostate cancer. It works by blocking the action of androgens (male hormones) that can promote the growth of cancer cells. This drug is particularly used in cases where the cancer has spread to other parts of the body and is resistant to other treatments.

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research Global Trends in Research of Androgen Receptor Associated With Breast Cancer From 2011 to 2020: A Scientometric Analysis

5 citations , June 2022 in “Frontiers in Endocrinology”

Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.

research TMPRSS2, Required for SARS-CoV-2 Entry, Is Downregulated in Lung Cells by Enzalutamide, a Prostate Cancer Therapeutic

2 citations , June 2020 in “Research Square (Research Square)”

A prostate cancer drug can lower the levels of a protein that the coronavirus uses to enter lung cells.

research Recent Discoveries and Developments of Androgen Receptor-Based Therapy for Prostate Cancer

17 citations , January 2015 in “MedChemComm”

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Androgenic Effects on Ventricular Repolarization: A Translational Study from Pharmacovigilance Databases to iPSC-Cardiomyocytes

research Androgenic Effects on Ventricular Repolarization: A Translational Study from Pharmacovigilance Databases to iPSC-Cardiomyocytes

October 2019 in “European heart journal”

Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.

research Cortexolone 17α-Propionate (Clascoterone) Is an Androgen Receptor Antagonist in Dermal Papilla Cells In Vitro

4 citations , February 2019 in “PubMed”

Clascoterone may be an effective topical treatment for hair loss.

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community Why you should use 0.5mg Dut instead of 1mg Fin

in Finasteride/Dutasteride 45 upvotes 3 years ago

The comparison of 0.5mg dutasteride and 1mg finasteride for treating hair loss in men with androgenetic alopecia, with discussion of which is more effective and has fewer side effects.

community [Research] RU-58841/Pyrilutamide and impacts on male fertility

in Research/Science 6 upvotes 2 years ago

The drugs RU-58841, Pyrilutamide (KX-826), Apalutamide, Enzalutamide, and Darolutamide, which are nonsteroidal antiandrogens (NSAA), potentially impacting male fertility. Pyrilutamide, similar to Enzalutamide, may have reversible effects on fertility.

community Pyrilutamide vs enzalutamide. Same thing?( Especially for biochemists, farmacologists)

in Research/Science 17 upvotes 3 years ago

Researching whether pyri and enza, which are stereoisomers of each other, share the same features related to CNS penetration/GABA Inhibition; safety and efficacy when used topically at 0.5-1%; and cost comparison between the two treatments.

community Is Pyrilutamide the real deal and if so when will it actually be available?

in Chat 21 upvotes 3 years ago

Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

community I'll defeat the norwood reaper with kitchen sink light

in Treatment 27 upvotes 3 years ago

A user who is using a combination of oral and topical treatments, including finasteride, minoxidil, pyrilutamide, dutasteride, microneedling, and ketoconazole shampoo in order to combat hair loss. Another user gave the original poster a word of warning about overusing the ketoconazole shampoo.

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